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Picture of 2,6-Difluorobenzenesulfonyl chloride

2,6-Difluorobenzenesulfonyl chloride

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Origin: China

Cas No: 60230-36-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    60230-36-6
    Other Names:
    2,6-Difluorobenzenesulfonyl chloride
    MF:
    C6H3ClF2O2S
    EINECS No.:
    626-498-5
    Place of Origin:
    Shandong, China
    Type:
    Pharmaceutical Intermediates
    Purity:
    98%
    Brand Name:
    Natural Micron
    Model Number:
    60230-36-6
    Application:
    Pharmaceutical Intermediate
    Appearance:
    White powder, White powder
    Product name:
    2,6-Difluorobenzenesulfonyl chloride
    Grade:
    Pharmaceutical Grade
    Assay:
    98%
    MOQ:
    1KG
    Certificate:
    COA
    Shelf life:
    2 Years
    Package:
    Aluminum Foil Bag
    CAS:
    60230-36-6
    Packing:
    1kg

    Packaging&Delivery

    Packaging Details
    Aluminium foil bag, Carton, Drum
    Port
    any port in China
    Lead Time:
    Quantity(Kilograms)1 - 50>50
    Est. Time(days)5To be negotiated
  • Property

    CAS No.: 60230-36-6 Formula: C6H3ClF2O2S Molecular Weight: 212.60200

    Description

    2,6-Difluorobenzenesulfonyl chloride is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. 2,6-Difluorobenzenesulfonyl chloride is also a potential inhibitor of zinc proteases.

    Basic Info

    Chemical Name 2,6-Difluorobenzenesulfonyl chloride
    Synonyms

    2,6-difluorobenzene-1-sulfonyl chloride;
    2,6-difluoro-benzenesulfonyl chloride;
    2,6-difluorophenylsulfonyl chloride;
    2,6-difluorobenzene-sulphonyl chloride;
    F9995-0416;
    2,5-DIFLUORO-4-METHOXYPHENYL BORONIC ACID;

    CAS No. 60230-36-6
    Molecular Formula C6H3ClF2O2S
    Molecular Weight 212.60200
    PSA 42.52000
    LogP 2.97310

    Properties

    Appearance & Physical State clear yellow liquid
    Density 1.568
    Boiling Point 210ºC
    Flash Point >110ºC
    Refractive Index 1.526

    Safety Info

    Hazard Class 8
    Safety Statements S26-S36/37/39-S45
    HS Code 2916399090
    Packing Group II
    WGK Germany 3
    RIDADR UN 3265
    Risk Statements R34
    Hazard Codes C

    Synthesis Route

    1,3-difluorobenzene2,6-Difluorobenzenesulfonyl chloride

    Precursor

    1,3-difluorobenzene

    Downstream Product

    2,6-Difluorobenzenesulfonamide
    dabrafenib
    dabrafenib mesylate

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