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(2,5-dioxopyrrolidin-1-yl) (2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoate

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Origin: China

Cas No: 3391-99-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 3391-99-9 Formula: C18H22N2O6 Molecular Weight: 362.37700

Basic Info

Chemical Name	(2,5-dioxopyrrolidin-1-yl) (2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoate
Synonyms	Z-isoleucine-N-hydroxysuccinimide ester; Cbz-Ile-OSu; N-benzilossicarbonil-isoleucil-ossisuccinimide; Z-Ile-OSu; Z-L-Ile hydroxysuccinimide ester; Z-L-isoleucine hydroxysuccinimide ester; N-Z-L-isoleucine N-hydroxysuccinimide ester; N-Cbz-L-isoleucine N-hydroxysuccinimide ester; Z-L-Ile-OSu; N-benzyloxycarbonyl-L-isoleucine N-hydroxysuccinimide ester;
CAS No.	3391-99-9
Molecular Formula	C18H22N2O6
Molecular Weight	362.37700
PSA	102.01000
LogP	2.26350

Properties

Density	1.27g/cm3
Melting Point	111-112ºC
Refractive Index	1.561
Storage Condition	2-8ºC

Safety Info

WGK Germany	3

Synthesis Route

N-Hydroxysuccinimide+(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid→(2,5-dioxopyrrolidin-1-yl) (2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoate
(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid→(2,5-dioxopyrrolidin-1-yl) (2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoate
N,N'-Disuccinimidyl carbonate+(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid→(2,5-dioxopyrrolidin-1-yl) (2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoate

Precursor

N,N'-Disuccinimidyl carbonate
N-Hydroxysuccinimide
(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid

Downstream Product

Z-ILE-NH2
(2S,3S)-3-methyl-2-[[(2S,3S)-3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoic acid
3-methyl-2-[[3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]butanoic acid
H-ILE-VAL-OH

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