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Home > Chiral Compounds> (24R)-24,25-dihydroxycalciol
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(24R)-24,25-dihydroxycalciol

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Origin: China

Cas No: 55721-11-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 55721-11-4 Formula: C27H44O3 Molecular Weight: 416.63600

    Description

    A metabolite of Vitamin D, a possibly anti-inflammatory steroid.

    Basic Info

    Chemical Name (24R)-24,25-dihydroxycalciol
    Synonyms

    k-dr;
    Secalciferol;
    osteod;

    CAS No. 55721-11-4
    Molecular Formula C27H44O3
    Molecular Weight 416.63600
    PSA 60.69000
    LogP 5.70470

    Properties

    Density 1.06 g/cm3
    Boiling Point 571.1ºC at 760 mmHg
    Melting Point 63-65ºC
    Flash Point 241.5ºC
    Refractive Index 1.547
    Storage Condition Amber Vial, -20ºC Freezer, Under Inert Atmosphere

    Safety Info

    Safety Statements S28-S36/37-S45
    RIDADR UN 2811
    Risk Statements R28
    Hazard Codes T+
    Symbol GHS06, GHS08
    Caution Statement P260; P280; P284; P301 + P310; P310
    Signal Word Danger
    Hazard Declaration H301 + H311; H330; H372

    Synthesis Route

    →(24R)-24,25-dihydroxycalciol
    (1R,3aR,4S,7aR)-1-[(1R,4R)-4,5-dihydroxy-1,5-dimethylhexyl]-7a-methyl-octahydro-1H-inden-4-ol→(24R)-24,25-dihydroxycalciol
    →(24R)-24,25-dihydroxycalciol

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rat >10 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - rat >2 mg/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor



    (1R,3aR,4S,7aR)-1-[(1R,4R)-4,5-dihydroxy-1,5-dimethylhexyl]-7a-methyl-octahydro-1H-inden-4-ol
    (3β,5Z,7E,24R)-3-[(tert-butyldimethylsilyl)oxy]-9,10-secocholesta-5,7,10(19)-triene-24,25-diol cyclic 24,25-(1-methylethylidene acetal)

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