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2,4-Dichloroquinoline

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Origin: China

Cas No: 703-61-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 703-61-7 Formula: C9H5Cl2N Molecular Weight: 198.04900

Description

2,4-Dichloroquinoline is used in the synthesis of tRNA synthetase inhibitors with antibacterial activity against gram-positive bacteria. Also used in the preparation of arylquinolines displaying anthelmintic properties.

Basic Info

Chemical Name	2,4-Dichloroquinoline
Synonyms	Quinoline, 2,4-dichloro-; 2,4-dichloroquinoline;
CAS No.	703-61-7
Molecular Formula	C9H5Cl2N
Molecular Weight	198.04900
PSA	12.89000
LogP	3.54160

Properties

Density	1.407 g/cm3
Boiling Point	281ºC at 760 mmHg
Melting Point	52-54ºC
Flash Point	154.2ºC
Refractive Index	1.66

Safety Info

Safety Statements	S26; S36
HS Code	2933499090
Risk Statements	R36/37/38
Hazard Codes	Xi
Symbol	GHS05, GHS06
Caution Statement	P261; P280; P301 + P310; P305 + P351 + P338
Signal Word	Danger
Hazard Declaration	H301; H315; H318; H335

Synthesis Route

4-hydroxy-1-methylquinolin-2-one→4-chloro-1-methylquinolin-2-one+2,4-Dichloroquinoline
4-nitroquinoline N-oxide→4-Chloroquinoline+2,4-Dichloroquinoline
4-Hydroxy-2(1H)-quinolinone→2,4-Dichloroquinoline

Precursor

malonic acid
4-hydroxyquinolin-2(1H)-one
4-Hydroxy-2(1H)-quinolinone

Downstream Product

2-methoxy-3-(3-methylbut-2-enyl)-1H-quinolin-4-one
2,4-dichloroquinoline-3-carbaldehyde
4-chloro-2-phenylquinoline
2-Chloroquinolin-4-amine

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