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2,4-Dichloroquinazoline

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Origin: China

Cas No: 607-68-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 607-68-1 Formula: C8H4Cl2N2 Molecular Weight: 199.03700

Description

2,4-Dichloroquinazoline has been used as a reactant for the preparation of 1-methyl-1H-imidazole derivatives as Jak2 inhibitors.

Basic Info

Chemical Name	2,4-Dichloroquinazoline
Synonyms	2,4-dichlorchinazolin; 2,4-dichloro-quinazoline; dichloroquinazoline; 2,4-dichoroquinazoline; Quinazoline,2,4-dichloro; 2,4-Dichloroquinazol;
CAS No.	607-68-1
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.03700
PSA	25.78000
LogP	2.93660

Properties

Appearance & Physical State	colorless liquid/white crystalline powder
Density	1.486 g/cm3
Boiling Point	273.3ºC at 760 mmHg
Melting Point	117－121ºC
Flash Point	145.4ºC
Refractive Index	1.531

Safety Info

HS Code	2933990090

Synthesis Route

1-Methylpyrrolidine+Benzoyleneurea→2-Chloroquinazolin-4(3H)-one+2,4-Dichloroquinazoline
Benzoyleneurea→2,4-Dichloroquinazoline
bis(trichloromethyl) carbonate+2-aminobenzonitrile→2,4-Dichloroquinazoline

Precursor

2-Chloroquinazolin-4(3H)-one
2-aminobenzonitrile
Benzoyleneurea
bis(trichloromethyl) carbonate

Downstream Product

4-Hydroxyquinazoline
quinazoline-2,4-diamine
2-Chloro-4-(diethylamino)quinazoline
2-Chloro-4-(pyrrolidin-1-yl)quinazoline

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