Home > Heterocyclic Compounds> 2',3',5'-Tri-O-acetyluridine

2',3',5'-Tri-O-acetyluridine

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Origin: China

Cas No: 4105-38-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
4105-38-8
Other Names:
2',3',5'-Tri-O-acetyluridine
MF:
C15H18N2O9
EINECS No.:
223-881-5
Place of Origin:
Shandong, China
Type:
Pharmaceutical Intermediates
Purity:
99.0%min
Brand Name:
Xigema
Model Number:
Top Grade
Application:
Used
Appearance:
White Powder, powder
Product name:
2',3',5'-Tri-O-acetyluridine
CAS:
4105-38-8
Molecular weight:
370.31
Water:
0.5% Max.
Color:
White
Name:
2',3',5'-Tri-O-acetyluridine
Shelf life:
2 Years
Test Method:
HPLC
Packaging&Delivery
Packaging Details
25kg/drum
Port
QINGDAO PORT

Property

CAS No.: 4105-38-8 Formula: C15H18N2O9 Molecular Weight: 370.31100

Description

2’,3’,5’-Triacetyluridine is used in the treatment of Alzheimer’s disease in mice and provide neuroprotective effects. Shown to also decrease depressive symptoms and increases in brain pH bipolar patients.

Basic Info

Chemical Name	2',3',5'-Tri-O-acetyluridine
Synonyms	O2',O3',O5'-triacetyl-uridine; Uridine, 2‘,3‘,5‘-triacetate; TAU; Uridine triacetate; Uridine 2',3',5'-Triacetate; 2',3',5'-Tri-O-acety; 2`,3`,5`-Triacetyluridine; 2',3',5'-Tri-O-acetyl-rU; (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate; 2',3',5'-Tri0acetyluridine; 2’,3’,5’-Triacetyluridine; Tri-O-acetyl uridine; 2`,3`,5`-Tracetyluridine; Vistonuridine; 2',3',5'-trioacetyluridine; 2',3',5'-O-triacetyluridine;
CAS No.	4105-38-8
Molecular Formula	C15H18N2O9
Molecular Weight	370.31100
PSA	142.99000
LogP	-1.13950

Properties

Appearance & Physical State	white or almost white crystalline powder
Density	1.43g/cm3
Melting Point	124-134ºC
Refractive Index	1.552
Storage Condition	-20ºC

Synthesis Route

Acetic anhydride+uridine→2',3',5'-Tri-O-acetyluridine
4-thio-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-(3H)-pyrimidine-2,4-dione→2',3',5'-Tri-O-acetyluridine
2',3',5'-tri-O-acetyl-3-nitrouridine→2',3',5'-Tri-O-acetyluridine

Precursor

Acetic anhydride
2,3,5-tri-O-acetyl-D-ribofuranosyl 1-(N-phenyl)-2,2,2-trifluoroacetimidate
4-thio-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-(3H)-pyrimidine-2,4-dione
uridine

Downstream Product

4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one
5-bromouridine
cytidine
2,2'-O-Anhydro-(1-β-D-arabinofuranosyl)uracil

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