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2,3,4-Trimethoxyphenylboronic acid

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Origin: China

Cas No: 118062-05-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 118062-05-8 Formula: C9H13BO5 Molecular Weight: 212.00800

Description

(2,3,4-Trimethoxyphenyl)boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer

Basic Info

Chemical Name	2,3,4-Trimethoxyphenylboronic acid
Synonyms	2,3,4-Trimethoxybenzeneboronic acid; (2,3,4-Trimethoxyphenyl)boronic acid;
CAS No.	118062-05-8
Molecular Formula	C9H13BO5
Molecular Weight	212.00800
PSA	68.15000
LogP	-0.60780

Properties

Appearance & Physical State	solid
Density	1.21g/cm3
Boiling Point	371.1ºC at 760mmHg
Melting Point	74-79ºC
Flash Point	178.3ºC
Refractive Index	1.513
Vapor Pressure	3.65E-06mmHg at 25°C

Safety Info

Safety Statements	S26
HS Code	2931900090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

1-bromo-2,3,4-trimethoxybenzene→2,3,4-Trimethoxyphenylboronic acid
Tributyl borate+2,3,4-trimethoxyphenylmagnesium bromide→2,3,4-Trimethoxyphenylboronic acid

Precursor

Tributyl borate
2,3,4-trimethoxyphenylmagnesium bromide
1-bromo-2,3,4-trimethoxybenzene

Downstream Product

1,2,3-trimethoxy-4-(4-methoxy-2-nitrophenyl)benzene
Urolithin D
2,3,4-Trimethoxybenzonitrile
1,2,3-trimethoxybenzene

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