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2,3-dihydroxybenzoic acid

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Origin: China

Cas No: 303-38-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    303-38-8
    Other Names:
    CAS 303-38-8
    MF:
    C7H6O4
    EINECS No.:
    206-139-5
    Place of Origin:
    Shandong, China
    Type:
    Agrochemical Intermediates, Dyestuff Intermediates, Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
    Purity:
    99%
    Brand Name:
    Finerchem
    Model Number:
    303-38-8
    Application:
    Organic intermediate
    Appearance:
    White powder
    CAS:
    303-38-8
    Product name:
    2,3-Dihydroxybenzoic acid
    Assay:
    99%
    Brand:
    Finerchem

    Packaging&Delivery

    Packaging Details
    Aluminum foil bag for within 10kg
    Fiber drum for 10kg and more
    Shipping: By air, by sea or by courier (VIP account of TNT, DHL, Fedex and EMS)
    Port
    Shanghai or Qingdao

  • Property

    CAS No.: 303-38-8 Formula: C7H6O4 Molecular Weight: 154.12000

    Description

    2,3-Dihydroxybenzoic acid is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta. It is also abundant in the fruits of Flacourtia inermis. It is a dihydroxybenzoic acid, a type of organic compound. The colorless solid occurs naturally, being formed via the shikimate pathway. It is incorporated into various siderophores, which are molecules that strongly complex iron ions for absorption into bacteria. 2,3-DHB consists of a catechol group, which upon deprotonation binds iron centers very strongly, and the carboxylic acid group by which the ring attaches to various scaffolds via amide linkages. A famous high affinity siderophore is enterochelin, which contains three dihydroxybenzoyl substituents linked to the depsipeptide of serine.
    It is a potentially useful iron-chelating drug and has antimicrobial properties
    2,3-Dihydroxybenzoic acid is also a product of human aspirin metabolism.

    Basic Info

    Chemical Name 2,3-dihydroxybenzoic acid
    Synonyms

    2-pyrocatechuicacid;
    2,3-DIAMIDOXIMO-1,4-DIHYDROXYNAPHTHALENE;
    catecholcarboxylicacid;
    hydroxysalicylic acid;
    2,3-Dihydroxybenzoic acid;
    2,3 DHB;
    O-PYROCATECHUIC ACID;
    Catechol-3-carboxylic Acid;
    2,3-dihydroxybenzoate;
    2,3-Dihydroxybenzoic;
    Benzoic acid, 2,3-dihydroxy-;
    2,3-Dihydroxybenzoicacid;
    di-hydroxybenzoic acid;
    Pyrocatechol-3-carboxylic Acid;
    DOBK;
    pyrocatechuic acid;
    RARECHEM AL BE 0035;

    CAS No. 303-38-8
    Molecular Formula C7H6O4
    Molecular Weight 154.12000
    PSA 77.76000
    LogP 0.79600

    Properties

    Appearance & Physical State white crystalline powder
    Density 1.559 g/cm3
    Boiling Point 208ºC
    Melting Point 204-208ºC
    Flash Point 187.2ºC
    Storage Condition 2-8°C

    Safety Info

    RTECS DG8576490
    Safety Statements S26-S37/39
    HS Code 2918290000
    WGK Germany 2
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    salicylic acid→2,4-Dihydroxybenzoic acid+2,3-dihydroxybenzoic acid
    benzoic acid→2,3-dihydroxybenzoic acid+2,5-dihydroxybenzoic acid
    salicylic acid→2,3-dihydroxybenzoic acid+2,5-dihydroxybenzoic acid

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed Apieson L 140. 1372. isothermal

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Oral LD50 - Lethal dose, 50 percent kill Rodent - rabbit >3 gm/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    2,3-Dihydroxybenzonitrile
    carbon dioxide
    2,3-dihydroxybenzaldehyde
    ethyl 2,3-dihydroxybenzoate

    Downstream Product

    METHYL 2,4-DIMETHOXYBENZOATE
    3-benzoyloxy-2-hydroxybenzoic acid
    3-benzoyloxy-5-bromo-2-hydroxybenzoic acid
    methyl 5-bromo-2,3-dihydroxybenzoate

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