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Picture of 22-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506

22-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506

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Origin: China

Cas No: 134556-79-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 134556-79-9 Formula: C50H85NO10Si Molecular Weight: 888.29600

    Description

    Analog of iso-FK-506.

    Basic Info

    Chemical Name 22-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506
    Synonyms

    CAS No. 134556-79-9
    Molecular Formula C50H85NO10Si
    Molecular Weight 888.29600
    PSA 152.06000
    LogP 8.36510

    Synthesis Route

    33-O-tert-butyldimethylsilyl-22(S)-dihydro-FK-50622-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506
    33-O-tert-butyldimethylsilyl-22(S)-dihydro-FK-506+N,N'-Carbonyldiimidazole22-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506+33-O-tert-butyldimethylsilyl-22(S)-dihydro-FK-506-22,24-cyclic carbonate
    Tacrolimus22-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506

    Precursor

    tert-butyldimethylsilyl chloride
    N,N'-Carbonyldiimidazole
    33-O-tert-butyldimethylsilyl-22(S)-dihydro-FK-506
    33-O-tert.butyldimethylsilyl-FK-506

    Downstream Product

    iso-Tacrolimus

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