Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Intermediates> 2-Methylquinoline

2-Methylquinoline

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 91-63-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Property

CAS No.: 91-63-4 Formula: C10H9N Molecular Weight: 143.18500

Description

Quinaldine or 2-methylquinoline is a simple derivative of a heterocyclic compound quinoline.
Quinaldine has critical point at 787 K and 4.9 MPa and its refractive index is 1.8116.
It can be prepared from aniline and paraldehyde via Skraup synthesis or from aniline and crotonaldehyde via Doebner-von Miller variation of the Skraup reaction or extracted from coal tar.

Basic Info

Chemical Name	2-Methylquinoline
Synonyms	Quinoline, 2-methyl-; Quinaldine;
CAS No.	91-63-4
Molecular Formula	C10H9N
Molecular Weight	143.18500
PSA	12.89000
LogP	2.54320

Properties

Appearance & Physical State	light yellow ( colourless)
Density	1.058
Boiling Point	248ºC
Melting Point	-2ºC
Flash Point	79ºC
Refractive Index	1.6108-1.6138
Water Solubility	PRACTICALLY INSOLUBLE
Stability	Stable, but may be light sensitive. Combustible. Incompatible with strong oxidizing agents.
Storage Condition	Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Info

RTECS	UZ9625000
Hazard Class	6.1
Safety Statements	S26-S36/37/39-S45
HS Code	29334990
WGK Germany	3
Risk Statements	R21/22; R36/37/38; R68
Hazard Codes	Xn

Synthesis Route

2-Butanone, 4-hydroxy-4-(2-nitrophenyl)-→2-Methylquinoline+2-methyl-1-oxidoquinolin-1-ium
chloroform+N,N-Dimethyl-o-toluidine→quinoline+2-Methylquinoline
chloroform+N,N-Dimethyl-o-toluidine→quinoline+2-Methylquinoline

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Capillary	OV-101	140.	1294.	isothermal
Capillary	OV-101	160.	1308.	isothermal
Capillary	OV-101	140.	1294.	isothermal
Capillary	OV-101	160.	1308.	isothermal
Capillary	OV-101	150.	1293.	isothermal

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Administration onto the skin	Standard Draize test	Rodent - rabbit	500 mg/24H	-
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	1230 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Administration onto the skin	LD50 - Lethal dose, 50 percent kill	Rodent - rabbit	1870 uL/kg	1.Details of toxic effects not reported other than lethal dose value