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2-Methoxynicotinic Acid

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Origin: China

Cas No: 16498-81-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 16498-81-0 Formula: C7H7NO3 Molecular Weight: 153.13500

Basic Info

Chemical Name	2-Methoxynicotinic Acid
Synonyms	2-Methoxynicotinic acid; 2-Methoxy-3-pyridinecarboxylic Acid; 2-methoxypyridine-3-carboxylic acid;
CAS No.	16498-81-0
Molecular Formula	C7H7NO3
Molecular Weight	153.13500
PSA	59.42000
LogP	0.78840

Properties

Appearance & Physical State	white crystalline powder
Density	1.284 g/cm3
Boiling Point	285.5ºC at 760 mmHg
Melting Point	164-167ºC
Flash Point	126.5ºC
Vapor Pressure	0.0013mmHg at 25°C

Safety Info

Safety Statements	S26-S37/39
HS Code	2933399090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Hazard Declaration	H319
Signal Word	Warning
Symbol	GHS07
Caution Statement	P305 + P351 + P338

Synthesis Route

2-Chloronicotinic acid→2-Methoxynicotinic Acid
Methyl 2-methoxynicotinate→2-Methoxynicotinic Acid
2-Chloronicotinic acid+Sodium methoxide→2-Methoxynicotinic Acid

Precursor

Sodium methoxide
2-Chloronicotinic acid
Methyl 2-methoxynicotinate

Downstream Product

camptothecin
7-Ethyl-10-hydroxycamptothecin
1,1-dimethyl-5H-furo[3,4-c]pyridine-3,4-dione
4-chloro-1,1-dimethylfuro[3,4-c]pyridin-3-one

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