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2-Hydroxy-5-trifluoromethylpyridine

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Origin: China

Cas No: 33252-63-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 33252-63-0 Formula: C6H4F3NO Molecular Weight: 163.09700

Basic Info

Chemical Name	2-Hydroxy-5-trifluoromethylpyridine
Synonyms	2-hydroxy-5-(trifluoromethyl)pyridine; 5-Trifluoromethyl-pyridin-2-ol; 5-(Trifluoromethyl)pyridin-2-ol; 5-(TRIFLUOROMETHYL)-2(1H)-PYRIDONE; 5-Trifluoromethyl-Pyridin-2; 5-(Trifluoromethyl)-2-pyridinone; 5-(TRIFLUOROMETHYL)-2-PYRIDINOL; 5-(TrifluoroMethyl)-2-pyridone; 5-trifluoromethyl-2-hydroxypyridine; 5-TRIFLUOROMETHYL-2-(1H)-PYRIDINONE; 5-trifloromethyl-2-hydroxypyridine; 5-TRIFLOROMETHYL-2-(1H)-PYRIDINONE; 5-(Trifluoromethyl)pyridin-2-one;
CAS No.	33252-63-0
Molecular Formula	C6H4F3NO
Molecular Weight	163.09700
PSA	33.12000
LogP	1.80600

Properties

Appearance & Physical State	Yellow to brown powder
Density	1.423 g/cm3
Boiling Point	286.815ºC at 760 mmHg
Melting Point	145-149ºC
Flash Point	127.262ºC
Refractive Index	1.457

Safety Info

Safety Statements	S26-S36
HS Code	2933399090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Symbol	GHS07
Caution Statement	P261; P305 + P351 + P338
Signal Word	Warning
Hazard Declaration	H315; H319; H335

Synthesis Route

[(C5(CH3)5)IrCl(5-trifluoromethyl-2-hydroxypyridine(-H))]→2-Hydroxy-5-trifluoromethylpyridine
5-(trifluoromethyl)pyridin-2-yl pivalate→2-Hydroxy-5-trifluoromethylpyridine
2-Chloro-5-trifluoromethylpyridine→2-Hydroxy-5-trifluoromethylpyridine

Precursor

5-(trifluoromethyl)pyridin-2-yl pivalate
[(C5(CH3)5)IrCl(5-trifluoromethyl-2-hydroxypyridine(-H))]
2-Chloro-5-(trichloromethyl)pyridine
2-Chloro-5-trifluoromethylpyridine

Downstream Product

Taranabant
2-methyl-2-[5-(trifluoromethyl)pyridin-2-yl]oxypropanoic acid
[3-nitro-5-(trifluoromethyl)pyridin-2-yl]hydrazine
3-Bromo-2-hydroxy-5-trifluoromethylpyridine

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