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Home > Organophosphorus Compounds> 2-diphenylphosphorylacetohydrazide
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2-diphenylphosphorylacetohydrazide

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Origin: China

Cas No: 16543-10-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 16543-10-5 Formula: C14H15N2O2P Molecular Weight: 274.25500

    Basic Info

    Chemical Name 2-diphenylphosphorylacetohydrazide
    Synonyms

    diphenylphosphorylacetic acid hydrazide;
    Fosenazide;
    Phosphabenzide;
    2-(Diphenylphosphoryl)acetohydrazide;
    diphenylphosphinylacetic acid hydrazide;
    Fosenazida [INN-Spanish];
    Fosenazidum [INN-Latin];
    Diphenylphosphinyl acethydrazide;
    diphenylphosphinoacetic acid hydrazide;
    Gidifen;
    Hydifen;
    diphenylphosphinoylacetic hydrazide;
    ACETIC ACID,(DIPHENYLPHOSPHINYL)-,HYDRAZIDE;

    CAS No. 16543-10-5
    Molecular Formula C14H15N2O2P
    Molecular Weight 274.25500
    PSA 85.49000
    LogP 2.53100

    Properties

    Density 1.26g/cm3
    Boiling Point 477.4ºC at 760mmHg
    Flash Point 242.5ºC
    Refractive Index 1.604
    Vapor Pressure 2.8E-09mmHg at 25°C

    Safety Info

    HS Code 2931900090

    Synthesis Route

    ethyl 2-diphenylphosphorylacetate→2-diphenylphosphorylacetohydrazide
    2-chloroethoxy(diphenyl)phosphane→2-diphenylphosphorylacetohydrazide
    Chlorodiphenylphosphine→2-diphenylphosphorylacetohydrazide

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Rodent - mouse 315 mg/kg 1.Behavioral-somnolence (general depressed activity)
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - mouse 293 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intraperitoneal LD50 - Lethal dose, 50 percent kill Mammal - species unspecified 315 mg/kg 1.Behavioral-changes in motor activity (specific assay)
    2.Behavioral-antipsychotic
    3.Behavioral-analgesia

    Precursor

    oxirane
    Ethyl chloroacetate
    2-chloroethoxy(diphenyl)phosphane
    Chlorodiphenylphosphine

    Downstream Product

    2-diphenylphosphorylacetyl azide
    2-diphenylphosphoryl-N-[(E)-thiophen-2-ylmethylideneamino]acetamide
    2-diphenylphosphoryl-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]acetamide
    2-diphenylphosphoryl-N'-[(E)-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]acetohydrazide

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