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2'-Deoxy-5-fluorocytidine

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Origin: China

Cas No: 10356-76-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 10356-76-0 Formula: C9H12FN3O4 Molecular Weight: 245.20800

Basic Info

Chemical Name	2'-Deoxy-5-fluorocytidine
Synonyms	5-Fluoro-2′-deoxycytidine; 2'-DEOXY-5-FLUOROCYTIDINE; 5-Fluorodeoxycytidine; 5-Fluoro-2'-deoxycytidine;
CAS No.	10356-76-0
Molecular Formula	C9H12FN3O4
Molecular Weight	245.20800
PSA	110.60000
LogP	-0.81350

Properties

Appearance & Physical State	Fine white powder
Density	1.82g/cm3
Boiling Point	465ºC at 760mmHg
Melting Point	196ºC
Flash Point	235ºC
Refractive Index	70 ° (C=1, H2O)
Vapor Pressure	1.34E-10mmHg at 25°C

Safety Info

RTECS	HA3850000
HS Code	2934999090
Hazard Declaration	H302
Signal Word	Warning
Symbol	GHS07

Synthesis Route

1-(3,5-di-O-benzoyl-2-deoxy-β-D-ribofuranosyl)-5-fluoro-N4-p-toluoylcytosine→2'-Deoxy-5-fluorocytidine
5-fluoro-4-(1,2,4-triazol-1-yl)-1-(3,5-di-O-acetyl-2-deoxy-β-D-ribofuranosyl)-pyrimidine-2(1H)-one→2'-Deoxy-5-fluorocytidine
[(2R,3S,5R)-3-acetyloxy-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate→2'-Deoxy-5-fluorocytidine

Precursor

5-fluoro-2'-deoxyuridine
[(2R,3S,5R)-3-acetyloxy-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
1-(3,5-di-O-benzoyl-2-deoxy-β-D-ribofuranosyl)-5-fluoro-N4-p-toluoylcytosine
5-fluoro-4-(1,2,4-triazol-1-yl)-1-(3,5-di-O-acetyl-2-deoxy-β-D-ribofuranosyl)-pyrimidine-2(1H)-one

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