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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Intermediates> 2-chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine
Picture of 2-chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine

2-chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine

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Origin: China

Cas No: 127-88-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 127-88-8 Formula: C4H8Cl4NOP Molecular Weight: 258.89800

    Description

    An intermediate for the synthesis of antitumor drugs used in chemotherapy

    Basic Info

    Chemical Name 2-chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine
    Synonyms

    CAS No. 127-88-8
    Molecular Formula C4H8Cl4NOP
    Molecular Weight 258.89800
    PSA 30.12000
    LogP 3.35170

    Properties

    Density 1.509g/cm3
    Boiling Point 304.9ºC at 760 mmHg
    Flash Point 138.2ºC
    Refractive Index 1.501
    Vapor Pressure 0.000847mmHg at 25°C

    Safety Info

    HS Code 2931900090
    Packing Group II
    RIDADR UN 1759

    Synthesis Route

    Bis(2-chloroethyl)amine hydrochloride→2-chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine
    N,N-dichloroethanamine→2-chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine
    bis(2-chloroethyl)amine→2-chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine

    Precursor

    bis(2-chloroethyl)amine
    N,N-dichloroethanamine
    Bis(2-chloroethyl)amine hydrochloride

    Downstream Product

    N,N-bis(2-chloroethyl)-2-oxo-1,3-dihydro-1,3,2λ<sup>5</sup>-benzodiazaphosphol-2-amine
    N-[amino(but-3-enoxy)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine
    cyclophosphamide
    N,N-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-dioxaphosphinan-2-amine

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