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2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide

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Origin: China

Cas No: 133627-46-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
133627-46-0
MF:
C12H9Cl2N3O
EINECS No.:
1312995-182-4
Place of Origin:
China
Type:
Syntheses Material Intermediates
Purity:
99.0%min
Brand Name:
Hungsun
Application:
Organic Synthesis
Appearance:
light yellow powder
Package:
25kg/carton Drum
Packaging&Delivery
Packaging Details
25KG
Port
Shanghai
Lead Time:
Shipped in 0 days after payment

Property

CAS No.: 133627-46-0 Formula: C12H9Cl2N3O Molecular Weight: 282.12500

Description

An intermediate in the synthesis of Nivirapine.

Basic Info

Chemical Name	2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide
Synonyms	2-Chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide;
CAS No.	133627-46-0
Molecular Formula	C12H9Cl2N3O
Molecular Weight	282.12500
PSA	54.88000
LogP	3.41710

Properties

Appearance & Physical State	Pale yellow solid
Density	1.447 g/cm3
Boiling Point	369.848ºC at 760 mmHg
Melting Point	189-191ºC
Flash Point	177.478ºC
Refractive Index	1.656
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2933399090

Synthesis Route

2-Chloronicotinyl chloride+2-Chloro-3-amino-4-methyl pyridine→2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide
2-chloro-4-methyl-3-nitropyridine→2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide
2-Chloronicotinic acid→2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide

Precursor

2-Chloronicotinyl chloride
2-Chloronicotinic acid
2-Chloro-3-amino-4-methyl pyridine
2-chloro-4-methyl-3-nitropyridine

Downstream Product

N-(2-chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)pyridine-3-carboxamide
nevirapine
11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
11-ethyl-4,5-dimethyldipyrido[2,3-d:3',2'-f][1,4]diazepin-6-one

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