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2-Chloro-5-nitropyridine

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FOB Price $100.00

Origin: China

Cas No: 4548-45-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
4548-45-2
MF:
C5H3ClN2O2
Purity:
98.0%
Appearance:
Off-White to yellow powder
CAS:
4548-45-2
Product Name:
2-Chloro-5-nitropyridine
Assay:
98.0%
Packaging&Delivery
Selling Units:
Single item
Single package size:
20X20X30 cm
Single gross weight:
1.100 kg
Lead Time:
Quantity(Kilograms) 1 - 10 11 - 100 101 - 1000 >1000
Est. Time(days) 1 1 1 To be negotiated

Property

CAS No.: 4548-45-2 Formula: C5H3ClN2O2 Molecular Weight: 158.54300

Description

2-Chloro-5-nitropyridine is used in the synthesis of 4-(Benzoylaminophenoxy)phenol derivatives as androgen receptor antagonists. Also used in the preparation of novel VEGFR2 kinase inhibitors used in controlling angiogenesis.

Basic Info

Chemical Name	2-Chloro-5-nitropyridine
Synonyms	EINECS 224-908-3; 2-chloro-5-nitro-pyridine; 6-Chloro-3-nitropyridine; Pyridine, 2-chloro-5-nitro-; 3-nitro-6-chloropyridine; 2-chloro-5-nitroypyridine; Pyridine,2-chloro-5-nitro; 5-nitro-2-chloropyridine;
CAS No.	4548-45-2
Molecular Formula	C5H3ClN2O2
Molecular Weight	158.54300
PSA	58.71000
LogP	2.16640

Properties

Appearance & Physical State	Light yellow to beige Powder
Density	1.489 g/cm3
Boiling Point	256.6ºC at 760 mmHg
Melting Point	106-110ºC
Flash Point	109ºC
Refractive Index	1.587
Stability	Stable at room temperature in closed containers under normal storage and handling conditions.
Storage Condition	Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Info

RTECS	US7175000
Safety Statements	S26-S37/39
HS Code	2933399090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

3-nitro-1-oxidopyridin-1-ium→2-Chloro-5-nitropyridine+2-Chloro-3-nitropyridine
2-Hydroxy-5-nitropyridine→2-Chloro-5-nitropyridine
2-Methoxy-5-nitropyridine→2-Chloro-5-nitropyridine

Precursor

N,N-dimethyl-5-nitropyridin-2-amine
2-Hydroxy-5-nitropyridine
2-Ethoxy-5-nitropyridine
2-Methoxy-5-nitropyridine

Downstream Product

5-morpholin-4-ylpyridine-2-carboxylic acid
5-Nitropyridine-2-sulfonic acid
1-pyridin-2-ylpropan-1-one
(4-methylphenyl)-(6-pentylpyridin-3-yl)diazene

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