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2-Chloro-4-pyridylboronic acid

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Origin: China

Cas No: 458532-96-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 458532-96-2 Formula: C5H5BClNO2 Molecular Weight: 157.36300

Description

2-Chloropyridine-4-boronic Acid is a substrate in a peroxide mediated hydroxydeboronation providing good yields of halohydroxypyridines. It is also a reagent used to prepare IRAK-4 inhibitors.

Basic Info

Chemical Name	2-Chloro-4-pyridylboronic acid
Synonyms	2-Chloropyridine-4-boronic acid; 2-Chloro-4-pyridineboronic acid; 2-Chloro-4-pyridinylboronic acid; (2-chloropyridin-4-yl)boronic acid; 2-Chloro-4-pyridylboronic Acid;
CAS No.	458532-96-2
Molecular Formula	C5H5BClNO2
Molecular Weight	157.36300
PSA	53.35000
LogP	-0.58520

Properties

Appearance & Physical State	WHITE TO TAN POWDER
Density	1.41 g/cm3
Boiling Point	355.2ºC at 760 mmHg
Melting Point	155-163ºC
Flash Point	168.6ºC
Refractive Index	1.559

Safety Info

Safety Statements	S26
HS Code	2933399090
Risk Statements	R36/37/38
Hazard Codes	Xi
Symbol	GHS07
Signal Word	Warning
Hazard Declaration	H315; H319; H335
Caution Statement	P261; P305 + P351 + P338

Synthesis Route

4-Bromo-2-chloropyridine→2-Chloro-4-pyridylboronic acid

Precursor

4-Bromo-2-chloropyridine

Downstream Product

3-bromo-5-(2-chloropyridin-4-yl)pyridine
2-Chloropyridine-4-boronic acid pinacol ester
2-Chloro-4-hydroxypyridine
2-chloro-3-(2-chloropyridin-4-yl)pyridine

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