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2-Aminoacetophenone hydrochloride

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Origin: China

Cas No: 5468-37-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 5468-37-1 Formula: C8H10ClNO Molecular Weight: 171.62400

    Description

    Hydrohchloride Salt of α-Aminoacetophenone, used in the preparation og pseudopeptidic inhibitors of human sirtuins1-3. This action effectually displays antiproliferative protperties in cancer cells. Also used in the preparation of dual δ/μopiod receptor agonists in th

    Basic Info

    Chemical Name 2-Aminoacetophenone hydrochloride
    Synonyms

    Ethanone, 2-amino-1-phenyl-, hydrochloride;
    2-amino-1-phenylethanone,hydrochloride;

    CAS No. 5468-37-1
    Molecular Formula C8H10ClNO
    Molecular Weight 171.62400
    PSA 43.09000
    LogP 2.33030

    Properties

    Appearance & Physical State off-white crystalline powder
    Density 1.084g/cm3
    Boiling Point 247.3ºC at 760mmHg
    Melting Point 194ºC
    Flash Point 103.4ºC
    Storage Condition Refrigerator (+4ºC)

    Safety Info

    RTECS AM5940000
    Safety Statements S26-S37/39
    HS Code 2922399090
    WGK Germany 3
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    2-Bromoacetophenone→2-Aminoacetophenone hydrochloride
    Benzoylnitromethane→2-Aminoacetophenone hydrochloride
    2-azido-1-phenylethanone→2-Aminoacetophenone hydrochloride

    Precursor

    2-azido-1-phenylethanone
    (R)-N-tert-butanesulfinyl 2,2-diethoxy-2-phenylethylamine
    2-Bromoacetophenone
    Benzoylnitromethane

    Downstream Product

    4-(5-phenyl-1,3-oxazol-2-yl)benzoic acid
    [5-methyl-3-(trifluoromethyl)-1H-pyrrol-2-yl]-phenylmethanone
    4-(5-phenyl-1,3-oxazol-2-yl)benzonitrile
    N-phenacylbenzamide

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