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2-Amino-6-chloropurine-9-riboside

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Origin: China

Cas No: 2004-07-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
2004-07-1
Other Names:
2-Amino-6-chloropurine-9-riboside
MF:
C10H12ClN5O4, C10H12ClN5O4
EINECS No.:
217-905-3
Place of Origin:
Shandong, China
Type:
Agrochemical Intermediates
Purity:
99.5%
Brand Name:
Natural Micron Pharm Tech
Model Number:
2004-07-1
Application:
Agrochemical Intermediates, Pharm Intermediates
Appearance:
White powder, White powder
Product Name:
2-Amino-6-chloropurine-9-riboside
CAS:
2004-07-1
Melting Point:
165-167 °C (dec.)(lit.)
EINECS:
217-905-3
Solubility:
Soluble in water
Storage:
Cool dried place
form:
Powder
Packaging&Delivery
Packaging Details
1kg/Aluminium foil bag
25kg/drum
25kg/carton
Port
Shanghai/Qingdao/Shenzhen
Lead Time:
Quantity(Kilograms) 1 - 10 >10
Est. Time(days) 7 To be negotiated

Property

CAS No.: 2004-07-1 Formula: C10H12ClN5O4 Molecular Weight: 301.68600

Description

6-Substituted purines; a novel class of inhibitors of endogenous protein degradation.

Basic Info

Chemical Name	2-Amino-6-chloropurine-9-riboside
Synonyms	(−)-2-Amino-6-chloropurine riboside 6-Chloroguanine riboside; 6-Chloroguanineriboside; 2-Amino-6-chloro-9-(β-D-ribofuranosyl)purine; 6-CHLOROGUANINE RIBOSIDE; (−)-2-Amino-6-chloropurine riboside; 6-CHLOROGUANOSINE; 2-Amino-6-chloropurine Riboside; 6-Chloroguanine nucleoside; 6-CHLOROADENOSINE; 6-Chloroguanosine2; 2-Amino-6-chloropurine-9--D-riboside;
CAS No.	2004-07-1
Molecular Formula	C10H12ClN5O4
Molecular Weight	301.68600
PSA	139.54000
LogP	-0.74540

Properties

Appearance & Physical State	white to off-white crystalline powder
Density	2.19 g/cm3
Boiling Point	729.9ºC at 760 mmHg
Melting Point	166-167ºC
Flash Point	395.2ºC
Refractive Index	-38 ° (C=0.1, H2O)
Storage Condition	-20ºC
Vapor Pressure	2.3E-22mmHg at 25°C

Safety Info

Safety Statements	S24/25
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

Methanol+2-amino-6-chloro-9-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine→2-Amino-6-chloropurine-9-riboside+(2R,3S,4R,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
7-methylguanosine iodide+6-chloroguanine→2-Amino-6-chloropurine-9-riboside+2-amino-7-methyl-1,7-dihydro-6H-purin-6-one
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate→2-Amino-6-chloropurine-9-riboside

Precursor

6-chloroguanine
disodium,[(2R,3R)-2,3,5-trihydroxy-4-oxopentyl] phosphate
(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
7-methylguanosine iodide

Downstream Product

[(2S,5R)-5-(2,6-diaminopurin-9-yl)oxolan-2-yl]methanol
2-Aminopurine Riboside
[(2S,5R)-5-(2,6-diaminopurin-9-yl)-2,5-dihydrofuran-2-yl]methanol
(2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

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