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2-(2,6-difluorophenyl)-2-hydroxyacetic acid

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Origin: China

Cas No: 207981-50-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 207981-50-8 Formula: C8H6F2O3 Molecular Weight: 188.12800

Basic Info

Chemical Name	2-(2,6-difluorophenyl)-2-hydroxyacetic acid
Synonyms	2,6-Difluoromandelic acid; (2,6-DIFLUORO-PHENYL)-HYDROXY-ACETIC ACID; 2,5-DIFLUORO-NICOTINIC ACID; (2,6-Difluorophenyl)(hydroxy)acetic acid;
CAS No.	207981-50-8
Molecular Formula	C8H6F2O3
Molecular Weight	188.12800
PSA	57.53000
LogP	1.08280

Properties

Density	1.522g/cm3
Boiling Point	299.3ºC at 760 mmHg
Melting Point	142-145ºC
Flash Point	134.8ºC
Refractive Index	1.542
Vapor Pressure	0.000539mmHg at 25°C

Safety Info

Safety Statements	S26-S36
HS Code	2918199090
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

Trimethylsilyl Cyanide+2,6-Difluorobenzaldehyde→2-(2,6-difluorophenyl)-2-hydroxyacetic acid
4-Cyanobenzaldehyde→2-(2,6-difluorophenyl)-2-hydroxyacetic acid+4-carboxymandelic acid
2-(Trifluoromethyl)benzaldehyde→2-(2,6-difluorophenyl)-2-hydroxyacetic acid+2-hydroxy-2-[2-(trifluoromethyl)phenyl]acetic acid

Precursor

Pentafluorobenzaldehyde
2,6-Difluorobenzaldehyde
Trimethylsilyl Cyanide
2-(Trifluoromethyl)benzaldehyde

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