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Picture of 2-(1,3-benzodioxol-5-yl)ethanamine

2-(1,3-benzodioxol-5-yl)ethanamine

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Origin: China

Cas No: 1484-85-1

Specification: 99%min

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 1484-85-1 Formula: C9H11NO2 Molecular Weight: 165.18900

    Description

    3,4-Methylenedioxyphenethylamine (MDPEA), also known as homopiperonylamine, is a substituted phenethylamine formed by adding a methylenedioxy group to phenethylamine. It is structurally similar to MDA, but without the methyl group at the alpha position.
    According to Alexander Shulgin in his book PiHKAL, MDPEA appears to be biologically inactive. This is likely because of extensive first-pass metabolism by the enzyme monoamine oxidase. However, if MDPEA were either used in high enough of doses (e.g., 1-2 grams), or in combination with a monoamine oxidase inhibitor (MAOI), it is probable that it would become sufficiently active, though it would likely have a relatively short duration of action. This idea is similar in concept to the use of selective MAOA inhibitors and selective MAOB inhibitors in augmentation of dimethyltryptamine (DMT) and phenethylamine (PEA), respectively.

    Basic Info

    Chemical Name 2-(1,3-benzodioxol-5-yl)ethanamine
    Synonyms

    homopiperonylamine;
    1,3-Benzodioxole-5-ethanamine;
    Methylenedioxyphenylethylamine;
    Benzo-1,3-dioxole-5-ethylamine;
    3,4-Methylenedioxyphenethylamine;
    Phenethylamine,3,4-methylenedioxy;
    2-[3,4-(methylenedioxyphenyl)]ethylamine;
    EINECS 216-060-8;
    3,4-methylenedioxyphenylethylamine;
    Methylenedioxyphenethylamine;

    CAS No. 1484-85-1
    Molecular Formula C9H11NO2
    Molecular Weight 165.18900
    PSA 44.48000
    LogP 1.61680

    Properties

    Appearance & Physical State Colourless Liquid
    Density 1.204 g/c3
    Boiling Point 274.3ºCat 760 mmHg
    Melting Point −131.5-−131 °C(lit.)
    Flash Point 129.8ºC
    Refractive Index 1.561
    Vapor Pressure 0.000618mmHg at 25°C

    Safety Info

    Hazard Class 3
    Safety Statements S36/37; S61
    HS Code 2935009090
    Packing Group II
    WGK Germany 3
    RIDADR UN 3295 3/PG 2
    Risk Statements R11; R43; R51/53
    Hazard Codes F; Xi; N

    Synthesis Route

    benzyl N-[2-(benzo[1,3]dioxol-5-yl)ethyl]carbamate2-(1,3-benzodioxol-5-yl)ethanamine
    3,4-Methylenedioxy-beta-nitrostyrene2-(1,3-benzodioxol-5-yl)ethanamine
    3-(1,3-benzodioxol-5-yl)propanamide2-(1,3-benzodioxol-5-yl)ethanamine

    Precursor

    benzyl N-[2-(benzo[1,3]dioxol-5-yl)ethyl]carbamate
    3,4-Methylenedioxy-beta-nitrostyrene
    3,4-(Methylenedioxy)phenylacetonitrile
    5-(2-Nitroethyl)-1,3-benzodioxole

    Downstream Product

    canadine
    1-[2-(1,3-benzodioxol-5-yl)ethyl]pyrrolidine-2,5-dione
    5H-[1,3]dioxolo[4,5-f]indole
    tyramine

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