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2-(1,3-benzodioxol-5-yl)ethanamine

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Origin: China

Cas No: 1484-85-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 1484-85-1 Formula: C9H11NO2 Molecular Weight: 165.18900

Description

3,4-Methylenedioxyphenethylamine (MDPEA), also known as homopiperonylamine, is a substituted phenethylamine formed by adding a methylenedioxy group to phenethylamine. It is structurally similar to MDA, but without the methyl group at the alpha position.
According to Alexander Shulgin in his book PiHKAL, MDPEA appears to be biologically inactive. This is likely because of extensive first-pass metabolism by the enzyme monoamine oxidase. However, if MDPEA were either used in high enough of doses (e.g., 1-2 grams), or in combination with a monoamine oxidase inhibitor (MAOI), it is probable that it would become sufficiently active, though it would likely have a relatively short duration of action. This idea is similar in concept to the use of selective MAOA inhibitors and selective MAOB inhibitors in augmentation of dimethyltryptamine (DMT) and phenethylamine (PEA), respectively.

Basic Info

Chemical Name	2-(1,3-benzodioxol-5-yl)ethanamine
Synonyms	homopiperonylamine; 1,3-Benzodioxole-5-ethanamine; Methylenedioxyphenylethylamine; Benzo-1,3-dioxole-5-ethylamine; 3,4-Methylenedioxyphenethylamine; Phenethylamine,3,4-methylenedioxy; 2-[3,4-(methylenedioxyphenyl)]ethylamine; EINECS 216-060-8; 3,4-methylenedioxyphenylethylamine; Methylenedioxyphenethylamine;
CAS No.	1484-85-1
Molecular Formula	C9H11NO2
Molecular Weight	165.18900
PSA	44.48000
LogP	1.61680

Properties

Appearance & Physical State	Colourless Liquid
Density	1.204 g/c3
Boiling Point	274.3ºCat 760 mmHg
Melting Point	−131.5-−131 °C(lit.)
Flash Point	129.8ºC
Refractive Index	1.561
Vapor Pressure	0.000618mmHg at 25°C

Safety Info

Hazard Class	3
Safety Statements	S36/37; S61
HS Code	2935009090
Packing Group	II
WGK Germany	3
RIDADR	UN 3295 3/PG 2
Risk Statements	R11; R43; R51/53
Hazard Codes	F; Xi; N

Synthesis Route

benzyl N-[2-(benzo[1,3]dioxol-5-yl)ethyl]carbamate→2-(1,3-benzodioxol-5-yl)ethanamine
3,4-Methylenedioxy-beta-nitrostyrene→2-(1,3-benzodioxol-5-yl)ethanamine
3-(1,3-benzodioxol-5-yl)propanamide→2-(1,3-benzodioxol-5-yl)ethanamine

Precursor

benzyl N-[2-(benzo[1,3]dioxol-5-yl)ethyl]carbamate
3,4-Methylenedioxy-beta-nitrostyrene
3,4-(Methylenedioxy)phenylacetonitrile
5-(2-Nitroethyl)-1,3-benzodioxole

Downstream Product

canadine
1-[2-(1,3-benzodioxol-5-yl)ethyl]pyrrolidine-2,5-dione
5H-[1,3]dioxolo[4,5-f]indole
tyramine

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