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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Intermediates> (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate
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(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate

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Origin: China

Cas No: 709031-45-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 709031-45-8 Formula: C7H14N2O4S Molecular Weight: 222.26200

    Basic Info

    Chemical Name (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate
    Synonyms

    (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carboxamide,methanesulfonic acid;

    CAS No. 709031-45-8
    Molecular Formula C7H14N2O4S
    Molecular Weight 222.26200
    PSA 118.86000
    LogP 1.28540

    Safety Info

    HS Code 2934999090

    Synthesis Route

    methanesulfonic acid+(1S,3S,5S)-tert-Butyl 3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate→(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate
    1-O-tert-butyl 2-O-ethyl (2S)-5-hydroxypyrrolidine-1,2-dicarboxylate→(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate
    Ethyl Boc-D-Pyroglutamate→(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate

    Precursor

    Ethyl Boc-D-Pyroglutamate
    1-O-tert-butyl 2-O-ethyl (2S)-5-hydroxypyrrolidine-1,2-dicarboxylate
    (1S,3S,5S)-tert-Butyl 3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
    methanesulfonic acid

    Downstream Product

    tert-butyl N-[(1S)-2-[(1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexan-2-yl]-1-(3-hydroxy-1-adamantyl)-2-oxoethyl]carbamate
    tert-butyl N-[2-(3-cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-(3-hydroxy-1-adamantyl)-2-oxoethyl]carbamate

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