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(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol

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Origin: China

CasNo: 83465-22-9

specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Description
  • Property

    CAS No.: 83465-22-9 Formula: C5H14N2O Molecular Weight: 118.17700

    Description

    Valiolamine is a aminocyclitol that exhibits potent alpha-D-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase.

    Basic Info

    Chemical Name (1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
    Synonyms

    Valiolamine hydrate;
    Valinolamine;
    valiolamine;

    CAS No. 83465-22-9
    Molecular Formula C5H14N2O
    Molecular Weight 118.17700
    PSA 72.27000
    LogP 0.30140

    Properties

    Density 1.623 g/cm3
    Boiling Point 368.6ºC at 760 mmHg
    Flash Point 176.7ºC

    Safety Info

    HS Code 2922199090

    Synthesis Route

    tetra-O-benzylvaliolamine(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
    (4aS,6S,6aS,8R,9R,10aR,10bS)-6-amino-8,9-dimethoxy-2,2,8,9-tetramethyloctahydro-4H-[1,4]dioxino[2',3':5,6]benzo[1,2-d][1,3]dioxin-4a-ol(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
    (1S,2S,3R,4S,5S)-1-azido-3-O-benzyl-5-((benzyloxy)methyl)cyclohexane-2,3,4,5-tetrol(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol

    Precursor

    (4aS,6S,6aS,8R,9R,10aR,10bS)-6-amino-8,9-dimethoxy-2,2,8,9-tetramethyloctahydro-4H-[1,4]dioxino[2',3':5,6]benzo[1,2-d][1,3]dioxin-4a-ol
    (1S,2S,3R,4S,5S)-1-azido-5-hydroxymethyl-2,3,4,5-tetrahydroxycyclohexane
    (1S,2S,3R,4S,5S)-1-azido-3-O-benzyl-5-((benzyloxy)methyl)cyclohexane-2,3,4,5-tetrol
    (1S,2S,4R,7S,9S,10S)-9-acetamido-12,12-dimethyl-4-phenyl-3,5,11,13-tetra-oxatricyclo[8.3.0.02,7]tridecane-7-ol

    Downstream Product

    Voglibose

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