Início > Chiral Compounds> (1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol

(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol

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Origem: China

Cas No: 83465-22-9

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Especificação de produtos
Descrição do produto

Property

CAS No.: 83465-22-9 Formula: C5H14N2O Molecular Weight: 118.17700

Description

Valiolamine is a aminocyclitol that exhibits potent alpha-D-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase.

Basic Info

Chemical Name	(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
Synonyms	Valiolamine hydrate; Valinolamine; valiolamine;
CAS No.	83465-22-9
Molecular Formula	C5H14N2O
Molecular Weight	118.17700
PSA	72.27000
LogP	0.30140

Properties

Density	1.623 g/cm3
Boiling Point	368.6ºC at 760 mmHg
Flash Point	176.7ºC

Safety Info

HS Code	2922199090

Synthesis Route

tetra-O-benzylvaliolamine→(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
(4aS,6S,6aS,8R,9R,10aR,10bS)-6-amino-8,9-dimethoxy-2,2,8,9-tetramethyloctahydro-4H-[1,4]dioxino[2',3':5,6]benzo[1,2-d][1,3]dioxin-4a-ol→(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
(1S,2S,3R,4S,5S)-1-azido-3-O-benzyl-5-((benzyloxy)methyl)cyclohexane-2,3,4,5-tetrol→(1S,2S,3R,4S,5S)-5-amino-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol

Precursor

(4aS,6S,6aS,8R,9R,10aR,10bS)-6-amino-8,9-dimethoxy-2,2,8,9-tetramethyloctahydro-4H-[1,4]dioxino[2',3':5,6]benzo[1,2-d][1,3]dioxin-4a-ol
(1S,2S,3R,4S,5S)-1-azido-5-hydroxymethyl-2,3,4,5-tetrahydroxycyclohexane
(1S,2S,3R,4S,5S)-1-azido-3-O-benzyl-5-((benzyloxy)methyl)cyclohexane-2,3,4,5-tetrol
(1S,2S,4R,7S,9S,10S)-9-acetamido-12,12-dimethyl-4-phenyl-3,5,11,13-tetra-oxatricyclo[8.3.0.02,7]tridecane-7-ol

Downstream Product

Voglibose

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