Home > Organosilicon Compounds> (1S,2S)-N-methyl-1-phenyl-1-[[(10R)-10-trimethylsilyl-9-borabicyclo[3.3.2]decan-9-yl]oxy]propan-2-amine

(1S,2S)-N-methyl-1-phenyl-1-[[(10R)-10-trimethylsilyl-9-borabicyclo[3.3.2]decan-9-yl]oxy]propan-2-amine

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Origin: China

Cas No: 848618-13-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 848618-13-3 Formula: C22H38BNOSi Molecular Weight: 371.44000

Basic Info

Chemical Name	(1S,2S)-N-methyl-1-phenyl-1-[[(10R)-10-trimethylsilyl-9-borabicyclo[3.3.2]decan-9-yl]oxy]propan-2-amine
Synonyms
CAS No.	848618-13-3
Molecular Formula	C22H38BNOSi
Molecular Weight	371.44000
PSA	21.26000
LogP	6.33640

Properties

Density	0.95g/cm3
Boiling Point	452.1ºC at 760 mmHg
Melting Point	130-134ºC
Flash Point	227.2ºC
Refractive Index	1.5

Safety Info

Safety Statements	S26
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

trimethyl((S)-1-phenyl-1-(((1S,5S,10R)-10-(trimethylsilyl)-9-borabicyclo[3.3.2]decan-9-yl)oxy)buta-2,3-dien-2-yl)silane+pseudoephedrine→(1S,2S)-N-methyl-1-phenyl-1-[[(10R)-10-trimethylsilyl-9-borabicyclo[3.3.2]decan-9-yl]oxy]propan-2-amine+(+)-(1S)-1-phenyl-2-(trimethylsilyl)-2,3-butadien-1-ol
(9-methoxy-9-borabicyclo[3.3.2]decan-10-yl)-trimethylsilane+pseudoephedrine→(1S,2S)-N-methyl-1-phenyl-1-[[(10R)-10-trimethylsilyl-9-borabicyclo[3.3.2]decan-9-yl]oxy]propan-2-amine
1-(Trimethylsilyl)-1-propyne→(1S,2S)-N-methyl-1-phenyl-1-[[(10R)-10-trimethylsilyl-9-borabicyclo[3.3.2]decan-9-yl]oxy]propan-2-amine

Precursor

9-METHOXY-9-BORABICYCLO[3.3.1]NONANE
pseudoephedrine
trimethyl((S)-1-phenyl-1-(((1S,5S,10R)-10-(trimethylsilyl)-9-borabicyclo[3.3.2]decan-9-yl)oxy)buta-2,3-dien-2-yl)silane
(9-methoxy-9-borabicyclo[3.3.2]decan-10-yl)-trimethylsilane

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