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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Intermediates> (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate
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(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate

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Origin: China

Cas No: 376608-71-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    376608-71-8
    Other Names:
    Ticagrelor Intermediates
    MF:
    C9H9F2N.C8H8O3
    EINECS No.:
    1308068-626-2
    Place of Origin:
    Zhejiang, China
    Type:
    Pharmaceutical Intermediates
    Purity:
    95% Min
    Brand Name:
    AFINE
    Model Number:
    AFI0320
    Application:
    Ticagrelor Intermediates
    Appearance:
    /
    Price:
    Negotiable & depends on quantity
    MOQ:
    According to regular packing
    COA & Document:
    Please send us inquiry

    Packaging&Delivery

    Packaging Details
    According to regular packing.
    Port
    Shanghai or Hangzhou or Beijing etc

  • Property

    CAS No.: 376608-71-8 Formula: C17H17F2NO3 Molecular Weight: 321.31900

    Description

    (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists for the prevention of thrombosis.

    Basic Info

    Chemical Name (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate
    Synonyms

    EX-7182;
    (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine,(2R)-2-hydroxy-2-phenylacetic acid;

    CAS No. 376608-71-8
    Molecular Formula C17H17F2NO3
    Molecular Weight 321.31900
    PSA 83.55000
    LogP 3.28430

    Safety Info

    HS Code 2922509090

    Synthesis Route

    trans-(1R,2S)-2-(3,4-difluorophenyl)-1-nitrocyclopropane+D-(-)-Mandelic acid→(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate
    1,2-difluorobenzene→(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate
    3-chloro-1-(3',4'-difluorophenyl)-propan-1-one→(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate

    Precursor

    1-(3',4'-difluorophenyl)-3-nitro-propan-1-one
    D-(-)-Mandelic acid
    1,2-difluorobenzene
    trans-(1R,2S)-2-(3,4-difluorophenyl)-1-nitrocyclopropane

    Downstream Product

    ticagrelor

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