Home > Chiral Compounds> (1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid

(1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid

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Origin: China

CasNo: 159622-10-3

specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Description

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CAS No.: 159622-10-3 Formula: C11H17NO4 Molecular Weight: 227.25700

Basic Info

Chemical Name	(1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid
Synonyms	(1R,2S)-2-ethenyl-1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopropane-1-carboxylic acid;
CAS No.	159622-10-3
Molecular Formula	C11H17NO4
Molecular Weight	227.25700
PSA	75.63000
LogP	1.93130

Properties

Density	1.171 g/cm3
Boiling Point	360.993ºC at 760 mmHg
Flash Point	172.123ºC
Refractive Index	1.508

Synthesis Route

methyl (1R,2S)-2-ethenyl-1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopropane-1-carboxylate→(1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid
methyl N-Boc-(1R,2S)-1-amino-2-vinylcyclopropane-carboxylate tosylate→(1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid
Cyclopropanecarboxylic acid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-ethenyl-, ethyl ester, (1R,2S)-→(1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid

Precursor

methyl N-Boc-(1R,2S)-1-amino-2-vinylcyclopropane-carboxylate tosylate
tert-butoxycarbonyl anhydride
methyl (1R,2S)-2-ethenyl-1-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopropane-1-carboxylate
Cyclopropanecarboxylic acid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-ethenyl-, ethyl ester, (1R,2S)-

Downstream Product

2-Methyl-2-propanyl {(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2 -vinylcyclopropyl}carbamate

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