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1H-pyrazole

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Origin: China

Cas No: 288-13-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
288-13-1
Other Names:
Pyrazole
MF:
C3H4N2
EINECS No.:
206-017-1
Type:
Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
98%
Application:
API
Appearance:
White to yellow
Test Method:
HPLC Test
Other Country:
GK
Packaging&Delivery
Packaging Details
Packing:1kg/bad,25kgs/drum Two plasti-bags inside and Paper-drums or as customer's requirements
Port
Major ports in China
Lead Time:
Quantity(Grams) 1 - 10000 >10000
Est. Time(days) 1 To be negotiated

Property

CAS No.: 288-13-1 Formula: C3H4N2 Molecular Weight: 68.07730

Description

1H-Pyrazole, is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing, muscle relaxing, psychoanaleptic, anticonvulsant, monoamineoxidase inhibiting, antidiabetic and antibacterial activities.

Basic Info

Chemical Name	1H-pyrazole
Synonyms	1H-Pyrazole; 1,2-Diazole; PYRAZOL; 2-PyrroMonazole; [3,2-c]pyrazole; Pyrazole; 1H-Pyrazol; PYRAZOLE,PURE; 1,2-DIAZOL; Pyrrazole;
CAS No.	288-13-1
Molecular Formula	C3H4N2
Molecular Weight	68.07730
PSA	28.68000
LogP	0.40970

Properties

Appearance & Physical State	White Crystal
Density	1.116 g/cm3
Boiling Point	186-188ºC
Melting Point	66-70ºC
Flash Point	87.5ºC
Refractive Index	1.4203 (20ºC)
Water Solubility	SOLUBLE
Stability	Stable under normal temperatures and pressures.
Storage Condition	Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure	0.887mmHg at 25°C

Safety Info

RTECS	UQ4900000
Hazard Class	6.1(b)
Safety Statements	S26-S37/39
HS Code	2933199090
WGK Germany	1
Packing Group	III
RIDADR	UN 2811
Risk Statements	R22; R36/37/38
Hazard Codes	Xn
Hazard Declaration	H302; H315; H319; H335
Symbol	GHS07
Caution Statement	P261; P305 + P351 + P338
Signal Word	Warning

Synthesis Route

α,γ-dipyrrolidinylglutaronitrile+2-Bromopropane→1H-pyrazole+3-Isopropyl-1H-pyrazole
N-Nitroso-N-allylbenzamid→1H-pyrazole+Allyl Benzoate
Benzene→1H-pyrazole+pyridazine

Precursor

2-Pyrazoline
tert-butyl pyrazole-1-carboxylate
2-(1-chloro-2-methylpropylidene)propanedinitrile
1H-Pyrazol-3(2H)-one

Downstream Product

ethyl 4-pyrazol-1-ylbutanoate
1-propylpyrazole
methyl 6-pyrazol-1-ylpyridine-3-carboxylate
1-(benzenesulfonyl)pyrazole

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