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Picture of 17-allyl-4,5α-epoxy-3-methoxy-morphin-7-en-6α-ol

17-allyl-4,5α-epoxy-3-methoxy-morphin-7-en-6α-ol

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Origin: China

Cas No: 56195-50-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 56195-50-7 Formula: C20H23NO3 Molecular Weight: 325.40200

    Description

    Nalodeine, also known more commonly as N-allylnorcodeine, is an opioid antagonist (specifically, an antagonist of the μ-opioid receptor) that was never marketed but is of notability in having been the first opioid antagonist to have been discovered. It was first reported in 1915, and this was followed by the clinical introduction of nalorphine (N-allylnormorphine) in 1954, naloxone (N-allyloxymorphone) in 1960, and naltrexone (N-methylcyclopropyloxymorphone) in 1963. Nalmefene (6-desoxy-6-methylene-naltrexone), another structurally related opioid antagonist derivative, was also subsequently introduced, in 1996. In animals, nalodeine both reverses morphine- and heroin-induced respiratory depression and acts as a respiratory stimulant in its own right (i.e., when given alone). Similarly to nalorphine, nalodeine has also been found to act as an agonist of the κ-opioid receptor.

    Basic Info

    Chemical Name 17-allyl-4,5α-epoxy-3-methoxy-morphin-7-en-6α-ol
    Synonyms

    CAS No. 56195-50-7
    Molecular Formula C20H23NO3
    Molecular Weight 325.40200
    PSA 41.93000
    LogP 1.99520

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