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1,4,5,6,7,7-hexachloro-3,3-bis(chloromethyl)-2-methylidenebicyclo[2.2.1]heptane

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Origin: China

Cas No: 8001-35-2

Specification: 99%min

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Supply Ability: 100 mt/month

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    CAS No.: 8001-35-2 Formula: C10H8Cl8 Molecular Weight: 411.79500

    Description

    Toxaphene was an insecticide used primarily for cotton in the southern United States during the late 1960s and 1970s. Toxaphene is a mixture of over 670 different chemicals and is produced by reacting chlorine gas with camphene. It can be most commonly found as a yellow to amber waxy solid.
    Toxaphene was banned in the United States in 1990 and was banned globally by the 2001 Stockholm Convention on Persistent Organic Pollutants. It is a very persistent chemical that can remain in the environment for 1–14 years without degrading, particularly in the soil.
    Testing performed on animals, mostly rats and mice, has demonstrated that toxaphene is harmful to animals. Exposure to toxaphene has proven to stimulate the central nervous system, as well as induce morphological changes in the thyroid, liver, and kidneys.
    Toxaphene has been shown to cause adverse health effects in humans. The main sources of exposure are through food, drinking water, breathing contaminated air, and direct contact with contaminated soil. Exposure to high levels of toxaphene can cause damage to the lungs, nervous system, liver, kidneys, and in extreme cases, may even cause death. It is thought to be a potential carcinogen in humans, though this has not yet been proven.

    Basic Info

    Chemical Name 1,4,5,6,7,7-hexachloro-3,3-bis(chloromethyl)-2-methylidenebicyclo[2.2.1]heptane
    Synonyms

    toxaphene;
    DSSTox_CID_1368;
    kamphochlor;
    camphechlor;
    chlorinated camphene;

    CAS No. 8001-35-2
    Molecular Formula C10H8Cl8
    Molecular Weight 411.79500
    PSA 0.00000
    LogP 6.62720

    Properties

    Appearance & Physical State yellow waxy solid
    Density 1.6
    Melting Point 65 - 90ºC
    Flash Point 4ºC
    Refractive Index 1.583
    Stability Stable. Incompatible with alkali, strong oxidizers. Heat and light sensitive.
    Storage Condition 2-8ºC

    Safety Info

    Hazard Class 6.1(b)
    Safety Statements 36/37-45-60-61-62-33-16-36-26
    Packing Group III
    RIDADR UN 2761
    Risk Statements R21; R25; R37/38; R40; R50/53; R67; R65; R38; R11; R36/37/38; R39/23/24/25; R23/24/25
    Hazard Codes C

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Administration onto the skin Standard Draize test Mammal - species unspecified 500 mg -
    Oral LDLo - Lowest published lethal dose Human 28 mg/kg 1.Behavioral-somnolence (general depressed activity)
    2.Behavioral-convulsions or effect on seizure threshold
    3.Behavioral-coma
    Oral TDLo - Lowest published toxic dose Rodent - rat 4186 mg/kg/13W-C 1.Liver-changes in liver weight
    2.Kidney, Ureter, Bladder-changes in bladder weight
    3.Biochemical-Enzyme inhibition, induction, or change in blood or tissue levels-hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

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