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Picture of 1,4-Dichloro-2-butyne

1,4-Dichloro-2-butyne

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Origin: China

Cas No: 821-10-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 821-10-3 Formula: C4H4Cl2 Molecular Weight: 122.98100

    Description

    1,4-Dichloro-2-butyne used in the synthesis of 1,4-disubstituted 1,2,3-triazoles. Also, it is used in the approach of the 20S-camptothecin family of antitumor agents.

    Basic Info

    Chemical Name 1,4-Dichloro-2-butyne
    Synonyms

    2-Butyne, 1,4-dichloro-;
    1,4-dichlorobut-2-yne;

    CAS No. 821-10-3
    Molecular Formula C4H4Cl2
    Molecular Weight 122.98100
    PSA 0.00000
    LogP 1.46740

    Properties

    Appearance & Physical State Clear brown liquid.
    Density 1.258
    Boiling Point 165-168ºC
    Melting Point -34.5ºC
    Flash Point 160ºC
    Refractive Index 1.503-1.506
    Stability Stable under normal temperatures and pressures.
    Storage Condition 2-8ºC

    Safety Info

    RTECS ER9600000
    Hazard Class 6.1
    Safety Statements S26-S28-S36/37/39-S38-S45
    HS Code 29032900
    WGK Germany 3
    Packing Group II
    RIDADR UN 2810
    Risk Statements R23/24/25; R36/37/38; R40
    Hazard Codes T

    Synthesis Route

    but-2-yne-1,4-diol4-chlorobut-2-yn-1-ol+1,4-Dichloro-2-butyne
    but-2-yne-1,4-bisoxycarbonylchloride1,4-Dichloro-2-butyne
    but-2-yne-1,4-diol1,4-Dichloro-2-butyne

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - mouse 56 mg/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    but-2-yne-1,4-diol
    thionyl dichloride
    pyridine
    hydrogen chloride

    Downstream Product

    5-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID
    N,N,N',N'-TETRAETHYL-2-BUTYNE-1,4-DIAMINE
    N,N,N',N'-tetramethylbut-2-yne-1,4-diamine
    Ethyl 5-methyl-1H-pyrrole-2-carboxylate

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