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(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetyl chloride

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Origem: China

Cas No: 6780-38-7

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 100 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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  • Especificação de produtos
  • Descrição do produto
  • Property

    CAS No.: 6780-38-7 Formula: C10H6ClNO3 Molecular Weight: 223.61300

    Basic Info

    Chemical Name (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetyl chloride
    Synonyms

    Phthalylglycyl chloride;
    2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo-;

    CAS No. 6780-38-7
    Molecular Formula C10H6ClNO3
    Molecular Weight 223.61300
    PSA 54.45000
    LogP 0.98590

    Properties

    Appearance & Physical State slight yellow to white crystalline powder
    Density 1.504 g/cm3
    Boiling Point 343.2ºC at 760 mmHg
    Refractive Index 1.614

    Safety Info

    Safety Statements S26-S36/37/39-S45
    HS Code 2925190090
    RIDADR UN 2923
    Risk Statements R25; R34
    Hazard Codes T

    Synthesis Route

    N-Phthaloylglycine(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetyl chloride
    tert-Butyl bromoacetate+3-Chloroanilinetert-butyl 2-[(3-chlorophenyl)-amino]acetate+(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetyl chloride
    phthalic anhydride(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetyl chloride

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Unreported LD50 - Lethal dose, 50 percent kill Mammal - species unspecified >1 gm/kg 1.Details of toxic effects not reported other than lethal dose value

    Precursor

    tert-Butyl bromoacetate
    ethyl 1,3-dioxoisoindole-2-carboxylate
    N-Phthaloylglycine
    3-Chloroaniline

    Downstream Product

    (8aS)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
    2-(1,3-dioxoisoindol-2-yl)-N-phenylacetamide
    N-Phthaloylglycine
    2-(2-oxopropyl)isoindole-1,3-dione

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