Home > Chiral Compounds> 1,2,3,4-Tetra-O-acetyl-β-D-glucuronic Acid Methyl Ester

1,2,3,4-Tetra-O-acetyl-β-D-glucuronic Acid Methyl Ester

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Origin: China

Cas No: 7355-18-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 7355-18-2 Formula: C15H20O11 Molecular Weight: 376.31300

Basic Info

Chemical Name	1,2,3,4-Tetra-O-acetyl-β-D-glucuronic Acid Methyl Ester
Synonyms	METHYL 1,2,3,4-TETRA-O-ACETYL-β-D-GLUCURONATE;
CAS No.	7355-18-2
Molecular Formula	C15H20O11
Molecular Weight	376.31300
PSA	140.73000
LogP	-0.75750

Properties

Appearance & Physical State	White Powder
Density	1.33 g/cm3
Boiling Point	412.3ºC at 760 mmHg
Melting Point	179ºC
Flash Point	178.4ºC
Refractive Index	8.0 ° (C=1, CHCl3)
Storage Condition	2-8ºC

Safety Info

WGK Germany	3

Synthesis Route

Methanol+(2R,3R,3aR,6aR)-2,3,6-trihydroxy-3,3a,6,6a-tetrahydro-2H-furo[3,2-b]furan-5-one→1,2,3,4-Tetra-O-acetyl-β-D-glucuronic Acid Methyl Ester
Methanol+(2R,3R,3aR,6aR)-2,3,6-trihydroxy-3,3a,6,6a-tetrahydro-2H-furo[3,2-b]furan-5-one→1,2,3,4-Tetra-O-acetyl-β-D-glucuronic Acid Methyl Ester
D-glucuronic acid methyl ester+acetyl chloride→1,2,3,4-Tetra-O-acetyl-β-D-glucuronic Acid Methyl Ester

Precursor

Sodium methoxide
Acetic anhydride
(2R,3R,3aR,6aR)-2,3,6-trihydroxy-3,3a,6,6a-tetrahydro-2H-furo[3,2-b]furan-5-one
D-glucuronic acid methyl ester

Downstream Product

estrone 3-O-(β-D-glucuronide)
17β-estradiol 3-glucosiduronic acid
1-Azido-1-deoxy-D-galacturonate 2,3,4-Triacetate Methyl Ester
Acetobromo-α-D-glucuronic Acid Methyl Ester

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