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Home > Boronic Acid Derivatives> 1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester
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1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester

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Origin: China

Cas No: 903550-26-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 903550-26-5 Formula: C14H23BN2O3 Molecular Weight: 278.15500

    Basic Info

    Chemical Name 1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester
    Synonyms

    1-(oxan-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole;

    CAS No. 903550-26-5
    Molecular Formula C14H23BN2O3
    Molecular Weight 278.15500
    PSA 45.51000
    LogP 1.88140

    Properties

    Density 1.16g/cm3
    Boiling Point 413.8ºC at 760mmHg
    Flash Point 204.1ºC
    Refractive Index 1.545

    Safety Info

    HS Code 2934999090

    Synthesis Route

    2,3-dimethylbutane-2,3-diol+1-(Tetrahydro-2H-Pyran-2-yl)-1H-Pyrazole→1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester
    2,3-dimethylbutane-2,3-diol+Triisopropyl Borate→1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester
    2,3-dimethylbutane-2,3-diol+Diisopropyl 1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-ylboronate→1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester

    Precursor

    1-(Tetrahydro-2H-Pyran-2-yl)-1H-Pyrazole
    2,3-dimethylbutane-2,3-diol
    Dihydropyran
    Diisopropyl 1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-ylboronate

    Downstream Product

    1-(Tetrahydro-2H-Pyran-2-yl)-1H-Pyrazole
    {2-fluoro-3-[2-(tetrahydropyran-2-yl)-2H-pyrazol-3-yl]phenyl}carbamic acid tert-butyl ester
    2,5-difluoro-N-{2-fluoro-3-[2-(tetrahydropyran-2-yl)-2H-pyrazol-3-yl]phenyl}-N-methoxymethylbenzenesulfonamide

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