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1-N-Boc-Pyrrolidin-2-ylboronic acid

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Origin: China

Cas No: 149682-75-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 149682-75-7 Formula: C9H18BNO4 Molecular Weight: 215.05500

Description

A boc-protected cyclic amine used in the preparation of heterocyclic boronic acid compounds.

Basic Info

Chemical Name	1-N-Boc-Pyrrolidin-2-ylboronic acid
Synonyms	2-Borono-1-pyrrolidinecarboxylicacid1-(1,1-dimethylethyl)ester;
CAS No.	149682-75-7
Molecular Formula	C9H18BNO4
Molecular Weight	215.05500
PSA	70.00000
LogP	0.75570

Properties

Density	1.15 g/cm3
Boiling Point	349.2ºC at 760 mmHg
Refractive Index	1.488
Vapor Pressure	2.89E-06mmHg at 25°C

Safety Info

HS Code	2933990090

Synthesis Route

trimethyl borate→1-N-Boc-Pyrrolidin-2-ylboronic acid
Hydrogen gas+N-Boc-2-pyrroleboronic acid→1-N-Boc-Pyrrolidin-2-ylboronic acid
1-Boc-Pyrrolidine→1-N-Boc-Pyrrolidin-2-ylboronic acid

Precursor

N-Boc-2-pyrroleboronic acid
Hydrogen gas
trimethyl borate
1-Boc-Pyrrolidine

Downstream Product

(1S,2S,3R,5S)-pinane-2,3-diyl (N-(1,1-dimethylethoxycarbonyl)pyrrolidin-2-yl)boronate

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