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1-Acetylindoline

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Origin: China

Cas No: 16078-30-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 16078-30-1 Formula: C10H11NO Molecular Weight: 161.20000

    Description

    1-(2,3-Dihydroindol-1-yl)ethanone is an intermediate used for preparation of triazolothiadiazepine dioxide derivatives, halo-substituted aromatic amides and [[(phenyl)piperazinyl]alkyl]indolyl]ethanone.

    Basic Info

    Chemical Name 1-Acetylindoline
    Synonyms

    N-Acetylindoline;
    1-(Indolin-1-yl)ethanone;
    1-(2,3-dihydroindol-1-yl)ethanone;

    CAS No. 16078-30-1
    Molecular Formula C10H11NO
    Molecular Weight 161.20000
    PSA 20.31000
    LogP 1.66060

    Properties

    Appearance & Physical State Off-white crystals
    Density 1.144 g/cm3
    Boiling Point 355.1ºC at 760 mmHg
    Melting Point 102-104ºC
    Flash Point 174.5ºC
    Refractive Index 1.575
    Vapor Pressure 3.2E-05mmHg at 25°C

    Safety Info

    RTECS NM1892500
    Safety Statements S22-S24/25
    HS Code 2933990090
    WGK Germany 3

    Synthesis Route

    1H-indole→indoline+1-Acetylindoline
    1H-indole+acetic acid→indoline+1-Acetylindoline
    indoline+acetyl chloride→1-Acetylindoline

    Precursor

    indoline
    acetyl chloride
    Acetic anhydride
    2-(2-((methoxycarbonyl)oxy)ethyl)phenyl trifluoromethanesulfonate

    Downstream Product

    1-(7-iodo-2,3-dihydroindol-1-yl)ethanone
    1-(5-iodo-2,3-dihydroindol-1-yl)ethanone
    7-Methoxy-1H-indole
    1-acetyl-2,3-dihydroindole-5-sulfonamide

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