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1-(5-chloro-2-hydroxy-4-methylphenyl)ethanone

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Origin: China

Cas No: 28480-70-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 28480-70-8 Formula: C9H9ClO2 Molecular Weight: 184.62000

Basic Info

Chemical Name	1-(5-chloro-2-hydroxy-4-methylphenyl)ethanone
Synonyms	5'-Chloro-2'-hydroxy-4'-Methylacetophenone; 2-Acetyl-4-chloro-5-methylphenol; 2-hydroxy-4-methyl-5-chloroacetophenone; 2-hydroxy-5-chloro-4-methylacetophenone; 4-Acetyl-2-chloro-5-hydroxytoluene; 4-methyl-5-chloro-2-hydroxyacetophenone; 5-chloro-4-methyl-2-hydroxyacetophenone;
CAS No.	28480-70-8
Molecular Formula	C9H9ClO2
Molecular Weight	184.62000
PSA	37.30000
LogP	2.55660

Properties

Density	1.25g/cm3
Boiling Point	137ºC / 15mmHg
Melting Point	70-73ºC(lit.)
Flash Point	132.2ºC
Refractive Index	1.562
Vapor Pressure	0.000889mmHg at 25°C

Safety Info

Safety Statements	26-36
HS Code	2914700090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

4-chloro-3-methylphenyl acetate→1-(5-chloro-2-hydroxy-4-methylphenyl)ethanone
4-chloro-6-[1-(hydroxyamino)ethylidene]-3-methylcyclohexa-2,4-dien-1-one→1-(5-chloro-2-hydroxy-4-methylphenyl)ethanone
4-Chloro-3-methylphenol+acetyl chloride→1-(5-chloro-2-hydroxy-4-methylphenyl)ethanone

Precursor

acetyl chloride
4-chloro-3-methylphenyl acetate
4-chloro-6-[1-(hydroxyamino)ethylidene]-3-methylcyclohexa-2,4-dien-1-one
acetic acid

Downstream Product

6-chloro-4-hydroxy-7-methylchromen-2-one
4-chloro-6-[1-(hydroxyamino)ethylidene]-3-methylcyclohexa-2,4-dien-1-one

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