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Picture of (‘±)-trans-1,2-Diaminocyclohexane

(‘±)-trans-1,2-Diaminocyclohexane

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Origin: China

Cas No: 1121-22-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    1121-22-8
    Other Names:
    (+/-)-trans-1,2-Diaminocyclohexane
    MF:
    C6H14N2
    EINECS No.:
    601-163-6
    Place of Origin:
    China
    Type:
    Pharmaceutical Intermediates
    Purity:
    99%
    Brand Name:
    Zichang
    Model Number:
    1121-22-8
    Application:
    Pharmaceutical Intermediates
    Appearance:
    white powder
    Molecular Weight:
    114.19
    Melting point:
    14-15 °C
    Boiling point:
    79-81 °C
    Density:
    0.951 g/mL
    Storage:
    Cool Dried Storage
    Form:
    Powder
    Color:
    White
    Package:
    25kg/bag/drum
    Shelf life:
    2 Years
    Flash point:
    156 °F

    Packaging&Delivery

    Packaging Details
    if order 1-20kg, aluminum foil bag+carton box.
    If order is more than 20kg,plastic bag+25kg carton drum
    Port
    shanghai /qingdao /tianjin
    Lead Time:
    Quantity(Kilograms)1 - 500>500
    Est. Time(days)5To be negotiated
  • Property

    CAS No.: 1121-22-8 Formula: C6H14N2 Molecular Weight: 114.18900

    Description

    trans-1,2-Diaminocyclohexane is an organic compound with the formula C6H10(NH2)2. This diamine is a building block for chiral ligands that are useful in asymmetric catalysis.
    A mixture of cis- and trans-1,2-diaminocyclohexane is produced by the hydrogenation of o-phenylenediamine. The racemic trans isomer [1:1 mixture of (1R,2R)-1,2-diaminocyclohexane and (1S,2S)-1,2-diaminocyclohexane] can be separated into the two enantiomers using enantiomerically pure tartaric acid as the resolving agent.
    Oxaliplatin, a complex of R,R-diaminocyclohexane, is an important anticancer drug.

    Basic Info

    Chemical Name (‘±)-trans-1,2-Diaminocyclohexane
    Synonyms

    trans-1,2-Cyclohexanediamine;
    (1R,2R)-cyclohexane-1,2-diamine;
    trans-1,2-Diaminocyclohexane;
    trans-Cyclohexane-1,2-diamine;
    (+/-)-Trans-1,2-Diaminocyclohexane;
    1,2-Cyclohexanediamine, (E)-;

    CAS No. 1121-22-8
    Molecular Formula C6H14N2
    Molecular Weight 114.18900
    PSA 52.04000
    LogP 1.61560

    Properties

    Appearance & Physical State Colorless liquid
    Density 0.951
    Boiling Point 79-81ºC (15 mmHg)
    Melting Point 14-15ºC
    Flash Point 68ºC
    Refractive Index 1.4885-1.4905
    Vapor Pressure 0.46mmHg at 25°C

    Safety Info

    Hazard Class 8
    Safety Statements S26-S36/37/39-S45
    HS Code 2942000000
    Packing Group II
    WGK Germany 3
    RIDADR UN 2735
    Risk Statements R34
    Hazard Codes C
    Hazard Declaration H314
    Symbol GHS05
    Signal Word Danger
    Caution Statement P280; P305 + P351 + P338; P310

    Synthesis Route

    trans-1,2-dinitrocyclohexane(‘±)-trans-1,2-Diaminocyclohexane
    7-Azabicyclo[4.1.0]heptane(‘±)-trans-1,2-Diaminocyclohexane
    1-nitrocyclohexene(‘±)-trans-1,2-Diaminocyclohexane

    Precursor

    cyclohexene
    1-nitrocyclohexene
    7-Azabicyclo[4.1.0]heptane
    trans-1,2-dinitrocyclohexane

    Downstream Product

    (1R,2R)-(-)-1,2-Diaminocyclohexane
    1-N,2-N-bis(7-chloroquinolin-4-yl)cyclohexane-1,2-diamine
    Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [SP-4-2-(1R-trans)]-
    dimethyl 3,3'-(((1R,2R)-cyclohexane-1,2-diyl)bis(azanediyl))bis(3-oxopropanoate)

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