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(+)-Pilocarpine hydrochloride

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Origin: China

CasNo: 54-71-7

specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Description
  • Property

    CAS No.: 54-71-7 Formula: C11H17ClN2O2 Molecular Weight: 244.71800

    Description

    Pilocarpine is a drug used to treat dry mouth and glaucoma. It is a parasympathomimetic alkaloid obtained from the leaves of tropical South American shrubs from the genus Pilocarpus. It is a non-selective muscarinic receptor agonist in the parasympathetic nervous system, which acts therapeutically at the muscarinic acetylcholine receptor M3 due to its topical application, e.g., in glaucoma and xerostomia.
    It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

    Basic Info

    Chemical Name (+)-Pilocarpine hydrochloride
    Synonyms

    (3S,4R);
    pilovisc;
    pilocarpine,2(3H)-furanone,3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)-methyl] monohydrochloride,(3S-cis);
    pilocar;
    amisturap;
    ami-pilo;
    Pilocarpine HCl;
    Sanpilo;
    (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)-methyl]dihydrofuran-2(3H)one hydrochloride;
    2(3H)-Furanone, 3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-, monohydrochloride, (3S-cis)-;
    Pilocarpine (Hydrochloride);
    pilocel;
    Akarpine;
    Salagen;

    CAS No. 54-71-7
    Molecular Formula C11H17ClN2O2
    Molecular Weight 244.71800
    PSA 44.12000
    LogP 1.96380

    Properties

    Appearance & Physical State powder white
    Boiling Point 431.8ºC at 760mmHg
    Melting Point 199-204ºC
    Flash Point 215ºC
    Refractive Index 1.584
    Water Solubility soluble
    Stability Stable under normal shipping and handling conditions.
    Storage Condition 2-8ºC

    Safety Info

    RTECS TK1450000
    Hazard Class 6.1
    Safety Statements S25-S45
    HS Code 2934999090
    Packing Group III
    WGK Germany 3
    RIDADR UN 1544
    Risk Statements R26/28
    Hazard Codes T+

    Synthesis Route

    (R)-3-ethylidene-4-[(1-methylimidazol-5-yl)methyl]tetrahydrofuran-2-one(+)-Pilocarpine hydrochloride

    Precursor

    (R)-3-ethylidene-4-[(1-methylimidazol-5-yl)methyl]tetrahydrofuran-2-one

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