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β-D-fructofuranose 2,6-bisphosphate

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Origin: China

Cas No: 79082-92-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 79082-92-1 Formula: C6H14O12P2 Molecular Weight: 340.11600

Description

Fructose-2,6-bisphosphate abbreviated Fru-2,6-P2, is a metabolite that allosterically affects the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1) to regulate glycolysis and gluconeogenesis. Fru-2,6-P2 is synthesized and broken down by the bifunctional enzyme phosphofructokinase 2/fructose-2,6-bisphosphatase (PFK-2/FBPase-2).
The synthesis of Fru-2,6-P2 is performed through a bifunctional enzyme containing both PFK-2 and FBPase-2, which is dephosphorylated, allowing the PFK-2 portion to phosphorylate fructose 6-phosphate using ATP. The breakdown of Fru-2,6-P2 is catalyzed by the phosphorylation of the bifunctional enzyme, which allows FBPase-2 to dephosphorylate Fructose-2,6-bisphosphate to produce Fructose 6-phosphate and Pi.
Reaction scheme of breakdown of fructose-2,6-bisphosphate to fructose-6-phosphate.

Basic Info

Chemical Name	β-D-fructofuranose 2,6-bisphosphate
Synonyms	beta-D-fructofuranose 2,6-bisphosphate; 2,6-Di-O-phosphono-β-D-fructofuranose;
CAS No.	79082-92-1
Molecular Formula	C6H14O12P2
Molecular Weight	340.11600
PSA	223.06000
LogP	-2.98580