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(S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid

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Origin: China

Cas No: 2280-27-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 2280-27-5 Formula: C5H11NO3 Molecular Weight: 133.14600

Basic Info

Chemical Name	(S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid
Synonyms	3-Hydroxy-L-Valine; 4-Methyl-L-threonine; 2-amino-3-hydroxy-3-methylbutanoic acid;
CAS No.	2280-27-5
Molecular Formula	C5H11NO3
Molecular Weight	133.14600
PSA	83.55000
LogP	-0.13050

Properties

Appearance & Physical State	white powder
Density	1.24 g/cm3
Boiling Point	317.3ºC at 760 mmHg
Melting Point	201 - 203ºC(decom)
Flash Point	145.7ºC
Refractive Index	1.503
Water Solubility	SOLUBLE
Vapor Pressure	3.25E-05mmHg at 25°C

Safety Info

Safety Statements	S24/25
HS Code	2922509090

Synthesis Route

2-hydroxy-2-methylpropanenitrile→(S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid
piperonal+(2S)-N-(2-benzoylphenyl)-1-benzylpyrrolidine-2-carboxamide→(S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid+(R)-threo-(3,4-methylenedioxy)-β-phenylserine
(2S)-N-(2-benzoylphenyl)-1-benzylpyrrolidine-2-carboxamide+acetone→(S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid+(R)-threo-(3,4-methylenedioxy)-β-phenylserine

Precursor

acetone
Glycine
(2S)-N-(2-benzoylphenyl)-1-benzylpyrrolidine-2-carboxamide
2-hydroxy-2-methylpropanenitrile

Downstream Product

Glycine
(2S)-3-hydroxy-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
L-valine

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