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(2R)-2-[tert-butyl(dimethyl)silyl]oxy-3-methylbutanoic acid

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Origin: China

Cas No: 119619-47-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 119619-47-5 Formula: C11H24O3Si Molecular Weight: 232.39200

Basic Info

Chemical Name	(2R)-2-[tert-butyl(dimethyl)silyl]oxy-3-methylbutanoic acid
Synonyms
CAS No.	119619-47-5
Molecular Formula	C11H24O3Si
Molecular Weight	232.39200
PSA	46.53000
LogP	3.11740

Synthesis Route

D-α-HYDROXYISOVALERIC ACID+tert-butyldimethylsilyl chloride→(2R)-2-[tert-butyl(dimethyl)silyl]oxy-3-methylbutanoic acid
(S)-(+)-2-Hydroxy-3-methylbutanoic acid+tert-butyldimethylsilyl chloride→(2R)-2-[tert-butyl(dimethyl)silyl]oxy-3-methylbutanoic acid
1-(furan-2-yl)-2-methylpropan-1-ol→(2R)-2-[tert-butyl(dimethyl)silyl]oxy-3-methylbutanoic acid

Precursor

tert-butyldimethylsilyl chloride
(R)-1-(2-furyl)-2-methyl-1-propanol
1-(furan-2-yl)-2-methylpropan-1-ol
(S)-(+)-2-Hydroxy-3-methylbutanoic acid

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