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Yohimbine

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Origem: China

Cas No: 146-48-5

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 50 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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  • Descrição do produto
  • Property

    CAS No.: 146-48-5 Formula: C21H26N2O3 Molecular Weight: 354.44300

    Description

    Yohimbine is an indole alkaloid derived from the bark of the Pausinystalia yohimbe tree in Central Africa. It is a veterinary drug used to reverse sedation in dogs and deer. Yohimbine has been studied as a potential treatment for erectile dysfunction but there is insufficient evidence to rate its effectiveness. Extracts from yohimbe have been marketed as dietary supplements for improving sexual function.

    Basic Info

    Chemical Name Yohimbine
    Synonyms

    APHRODINE;
    Yohimex;
    Yohimbin;
    Quebrachine;
    Aphrodyne;
    Quebrachin;
    Corynine;
    Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16α,17α)-;
    Yocon;
    Aphrosol;
    Yohimbine free base;
    methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;

    CAS No. 146-48-5
    Molecular Formula C21H26N2O3
    Molecular Weight 354.44300
    PSA 65.56000
    LogP 2.58500

    Properties

    Density 1.31 g/cm3
    Boiling Point 543ºC at 760 mmHg
    Melting Point 231-233 °C(lit.); 241 °C
    Flash Point 282.2ºC
    Refractive Index 1.66
    Vapor Pressure 1.27E-12mmHg at 25°C

    Safety Info

    RTECS ZG1000000
    Hazard Class 6.1(a)
    Safety Statements 27-36/37/39-45
    Packing Group II
    RIDADR UN 1544
    Risk Statements R23/24/25
    Hazard Codes T

    Synthesis Route

    (1R,2S,4aR,13bS,14aS)-methyl-2-hydroxy-1,2,4a,5,7,8,13,13b,14,14a-decahydroindolo[2',3':3,4]pyrido-[1,2-b]isoquinoline-1-carboxylateYohimbine
    (+)-yohimbinoneYohimbine
    (20β)-18,19-didehydroyohimban-17-oneYohimbine

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed SE-30 280. 3150. isothermal
    Capillary SE-30 - 3168. temperature ramp
    Packed OV-1 - 3130. temperature ramp
    Packed SE-30 - 3175. temperature ramp

    Precursor

    (+)-yohimbinone
    (20β)-18,19-didehydroyohimban-17-one
    (4aS,6S,7R,8aR)-2-(2-(1H-indol-3-yl)ethyl)-7-hydroxy-3-oxodecahydroisoquinolin-6-yl pivalate
    (1R,2S,4aR,13bS,14aS)-methyl-2-hydroxy-1,2,4a,5,7,8,13,13b,14,14a-decahydroindolo[2',3':3,4]pyrido-[1,2-b]isoquinoline-1-carboxylate

    Downstream Product

    Indole-2-carboxylic acid
    3-ethyl-1H-indole
    isoquinoline
    (2R)-2-(2,4,5-trichlorophenoxy)propanoic acid

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