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Urapidil Hydrochloride

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Origin: China

Cas No: 64887-14-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 64887-14-5 Formula: C20H30ClN5O3 Molecular Weight: 423.93700

Description

Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist Although an initial report suggested that urapidil was also an α2-adrenoceptor agonist, this was not substantiated in later studies that demonstrated it was devoid of agonist actions in the dog saphenous vein and the guinea-pig ileum. Unlike some other α1-adrenoceptor antagonists, urapidil does not elicit reflex tachycardia, and this may be related to its weak β1-adrenoceptor antagonist activity, as well as its effect on cardiac vagal drive. Urapidil is currently not approved by the U.S. Food and Drug Administration, but it is available in Europe.

Basic Info

Chemical Name	Urapidil Hydrochloride
Synonyms	6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethylpyrimidine-2,4-dione,hydrochloride;
CAS No.	64887-14-5
Molecular Formula	C20H30ClN5O3
Molecular Weight	423.93700
PSA	71.74000
LogP	1.59470

Properties

Appearance & Physical State	white or off-white crystalline powder
Boiling Point	549ºC at 760 mmHg
Melting Point	156-158ºC
Flash Point	285.8ºC
Storage Condition	Desiccate at RT