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(R)-2-Amino-3-cyclopropylpropanoic acid

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Origin: China

Cas No: 121786-39-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 121786-39-8 Formula: C6H11NO2 Molecular Weight: 129.15700

Description

D-Cyclopropylalanine is used in the synthesis of heterocyclo-fused [1,3]oxazepines and -thiazepines and analogs as inhibitors of neutral endopeptidase and angiotensin converting enzyme.

Basic Info

Chemical Name	(R)-2-Amino-3-cyclopropylpropanoic acid
Synonyms	(2R)-2-amino-3-cyclopropylpropanoic acid; D-Cyclopropylalinine; D-Cyclopropylalanine; 2-Cyclopropyl-D-alanine;
CAS No.	121786-39-8
Molecular Formula	C6H11NO2
Molecular Weight	129.15700
PSA	63.32000
LogP	0.89870

Properties

Density	1.218g/cm3
Boiling Point	258ºC at 760mmHg
Flash Point	109.9ºC
Refractive Index	1.496
Storage Condition	-15ºC
Vapor Pressure	0.00994mmHg at 25°C

Synthesis Route

(1S)-1-methyl-2-oxo-2-tetrahydro-1H-pyrrolylethyl N-(p-methoxyphenyl)-2-amino-3-cyclopropylpropanoate→(R)-2-Amino-3-cyclopropylpropanoic acid+(2S)-2-amino-3-cyclopropylpropanoic acid
2-acetamido-3-cyclopropylpropanoic acid→(R)-2-Amino-3-cyclopropylpropanoic acid+(2S)-2-amino-3-cyclopropylpropanoic acid
(1S)-1-methyl-2-oxo-2-tetrahydro-1H-pyrrolylethyl 2-bromo-3-cyclopropylpropanoate→(R)-2-Amino-3-cyclopropylpropanoic acid+(2S)-2-amino-3-cyclopropylpropanoic acid

Precursor

2-acetamido-3-cyclopropylpropanoic acid
(R)-2-Amino-3-cyclopropyl-N-((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-propionamide
Iodomethylcyclopropane
(S,S)-(+)-PSEUDOEPHEDRINE GLYCINAMIDE

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