Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> oxcarbazepine

oxcarbazepine

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 28721-07-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Quick Details
CAS No.:
28721-07-5
Other Names:
Oxcarbazepine
MF:
C15H12N2O2
EINECS No.:
249-188-8
Place of Origin:
Shandong, China
Type:
Antibiotic and Antimicrobial Agents
Grade Standard:
Medicine Grade
Usage:
Animal Pharmaceuticals
Brand Name:
QDXIGEMA
Model Number:
TOP
Purity:
99%
Product Name:
Oxcarbazepine
MW:
252.27
storage temp:
Store at RT
Color:
white
Form:
solid
Shelf life:
2 Years
Melting point:
215-216°C
solubility:
DMSO: ~9 mg/mL
Flash point:
2℃
Merck:
14,6929
Packaging&Delivery
Packaging Details
For small quantity: Bag
Commercial quantity: fiber drum
Port
Qingdao port

Property

CAS No.: 28721-07-5 Formula: C15H12N2O2 Molecular Weight: 252.26800

Description

Oxcarbazepine is an anticonvulsant drug primarily used in the treatment of epilepsy. There is some evidence for oxcarbazepine as a mood-stabilizing agent and thus, it can be used as add-on therapy for bipolar disorder in patients that have failed or are unable to tolerate approved treatments.
Common side effects include nausea, vomiting, dizziness, drowsiness, headache, double vision and trouble with walking. Although not common, anaphylaxis may occur. Due to its structural similarities to carbamazepine there is approximately a 25-30% chance of cross-reactivity between the two medications.
Oxcarbazepine is marketed as Trileptal by Novartis and available in some countries as a generic drug. There is also an extended-release formation marketed as Oxtellar XR by Supernus Pharmaceuticals.

Basic Info

Chemical Name	oxcarbazepine
Synonyms	10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide,Oxacarbazepine; 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide Oxacarbazepine; Oxecarb; OXCARBAMAZEPINE; Oxcarbapezine; Ocarbazepine; Oxetol; TRILEPTAL; Aurene; Oxcarbazepine; 10,11-Dihydro-10-oxo-5H-dibenzo[b,f]azepine-5-carboxamide; OXACARBAZEPINE;
CAS No.	28721-07-5
Molecular Formula	C15H12N2O2
Molecular Weight	252.26800
PSA	63.40000
LogP	3.40750

Properties

Appearance & Physical State	White to off-white crystalline powder
Density	1.329g/cm3
Boiling Point	457ºC
Melting Point	218 - 224ºC
Refractive Index	1.661
Vapor Pressure	1.52E-08mmHg at 25°C

Safety Info

RTECS	HN8445000
HS Code	2933990090
WGK Germany	3
Hazard Declaration	H302
Symbol	GHS07
Signal Word	Warning

Synthesis Route

licarbazepine→oxcarbazepine
10-Methoxy-5H-dibenzo[b,f]azepine+sodium cyanate→oxcarbazepine
10-Methoxycarbamazepine→oxcarbazepine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	TDLo - Lowest published toxic dose	Rodent - mouse	14300 mg/kg,female 6-18 day(s) after conception	1.Reproductive-Effects on Embryo or Fetus-fetotoxicity (except death, e.g., stunted fetus)