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(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate

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Origin: China

Cas No: 1020157-01-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 1020157-01-0 Formula: C48H44N6O6 Molecular Weight: 800.90000

Basic Info

Chemical Name	(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
Synonyms	1,3-Dioxol-2-one,4-(hydroxymethyl)-5-methyl; trityl olmesartan acetone solvate; (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]imidazole-5-carboxylate; (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl alcohol; 4-methyl-5-hydroxymethyl-2-oxo-1,3-dioxol-4-ene; 4-(hydroxymethyl)-5-methyl-1,3-dioxolenone; trityl olmesartan medoxomil; 4-hydroxymethyl-5-methyl-2-oxo-1,3-dioxole; (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-(4-(2-(trityltetrazol-5-yl)phenyl)phenylmethyl)-imidazole-5-carboxylate; 4-hydroxymethyl-5-methyl-1,3-dioxol-2-one;
CAS No.	1020157-01-0
Molecular Formula	C48H44N6O6
Molecular Weight	800.90000
PSA	151.30000
LogP	8.48360

Synthesis Route

N2-Trityl Olmesartan Acid+4-Cloromethyl-5-methyl-1,3-dioxol-2-one→(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
2-Propyl-1H-imidazole-4,5-dicarboxylic acid→(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
5-[2-[4-(bromomethyl)phenyl]phenyl]-2-trityltetrazole→(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate

Precursor

2-Propyl-1H-imidazole-4,5-dicarboxylic acid
N2-Trityl Olmesartan Acid
4-Cloromethyl-5-methyl-1,3-dioxol-2-one
5-[2-[4-(bromomethyl)phenyl]phenyl]-2-trityltetrazole

Downstream Product

Olmesartan medoxomil

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