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(4R,4aS,7S,7aR,12bS)-9-methoxy-3-methyl-1,2,4,7,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol

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Origin: China

Cas No: 4829-46-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 4829-46-3 Formula: C18H21NO4 Molecular Weight: 315.36400

Basic Info

Chemical Name	(4R,4aS,7S,7aR,12bS)-9-methoxy-3-methyl-1,2,4,7,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol
Synonyms	14-Hydroxycodeine; 14-Hydroxy-codein; 14-hydroxydihydrocodeine;
CAS No.	4829-46-3
Molecular Formula	C18H21NO4
Molecular Weight	315.36400
PSA	62.16000
LogP	0.55390

Properties

Density	1.43 g/cm3
Boiling Point	506.3ºC at 760 mmHg
Flash Point	260ºC
Refractive Index	1.694

Synthesis Route

Codeine→14-Hydroxy Codeinone+(4R,4aS,7S,7aR,12bS)-9-methoxy-3-methyl-1,2,4,7,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol
14-Hydroxy Codeinone→(4R,4aS,7S,7aR,12bS)-9-methoxy-3-methyl-1,2,4,7,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol
(+)-14β-bromocodeinone→(4R,4aS,7S,7aR,12bS)-9-methoxy-3-methyl-1,2,4,7,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol

Precursor

Codeine
(+)-14β-bromocodeine
Thebaine
(+)-14β-bromocodeinone

Downstream Product

dimethyl 2,3-diphenoxybutanedioate
[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] pentanoate
14-Hydroxy Codeinone
[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate

Hot tags: (4r,4as,7s,7ar,12bs)-9-methoxy-3-methyl-1,2,4,7,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,7-diol, China, manufacturers, suppliers, factory, wholesale, low price, high quality