Home > Heterocyclic Compounds> (4R-Cis)-6-Hydroxymethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid 1,1-Dimethylethyl Ester

(4R-Cis)-6-Hydroxymethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid 1,1-Dimethylethyl Ester

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Origin: China

Cas No: 124655-09-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
124655-09-0
Other Names:
N/A
MF:
C13H24O5
EINECS No.:
432-960-5
Place of Origin:
China
Type:
Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
99.0%min
Brand Name:
Sartort
Model Number:
APIs & Intermediates
Application:
Solvent
Appearance:
light yellow liquid, light yellow liquid
Packaging&Delivery
Packaging Details
1 Unit
Port
Any port in china
Lead Time:
Quantity(Kilograms) 1 - 1 >1
Est. Time(days) 3 To be negotiated

Property

CAS No.: 124655-09-0 Formula: C13H24O5 Molecular Weight: 260.32700

Description

A useful synthetic intermediate.

Basic Info

Chemical Name	(4R-Cis)-6-Hydroxymethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid 1,1-Dimethylethyl Ester
Synonyms	tert-Butyl (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate; tert-Butyl 2-[(4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate; (4R,6S)-6-Hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; (4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester; 2-[(4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic Acid tert-Butyl Ester; tert-Butyl (4R,6S)-6-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxane-4-acetate;
CAS No.	124655-09-0
Molecular Formula	C13H24O5
Molecular Weight	260.32700
PSA	64.99000
LogP	1.62070

Properties

Appearance & Physical State	Colorless to light yellow liquid
Density	1.03
Boiling Point	331ºC
Flash Point	113ºC
Refractive Index	1.442
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2932999099

Synthesis Route

tert-butyl 2-{(4R,6S)-6-[(benzyloxy)methyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetate→(4R-Cis)-6-Hydroxymethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid 1,1-Dimethylethyl Ester
tert-Butyl (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate→(4R-Cis)-6-Hydroxymethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid 1,1-Dimethylethyl Ester
tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate→(4R-Cis)-6-Hydroxymethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid 1,1-Dimethylethyl Ester

Precursor

1-methyl 6-tert.-butyl (2S,4R)-2,4-O-isopropylidene-2,4-dihydroxyadipate
tert-butyl 2-{(4R,6S)-6-[(benzyloxy)methyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetate
tert-Butyl (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate
tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate

Downstream Product

tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
sodium,(E,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoate
tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate
Rosuvastatin Lactone

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