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4-aminosalicylic acid

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Origin: China

Cas No: 65-49-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
Classification:
Sulfonic Acid
CAS No.:
65-49-6
Other Names:
3-Hydroxy-4-carboxyaniline
MF:
C7H7NO3
EINECS No.:
200-613-5
Place of Origin:
China
Purity:
99%
Appearance:
White crystalline
Application:
Organic chemical raw material
Brand Name:
ELIEVE
Model Number:
FJIOISJF7
Product Name:
4-Aminosalicylic acid
CAS:
65-49-6
Usage:
Organic chemical raw material
Molecular formula:
C7H7NO3
Sample:
Provide
Packing:
drum
Origin:
Weifang,China
Melting point:
135-145 °C(lit.)
Assay:
99%
Color:
white
Packaging&Delivery
Packaging Details
Liquid products :

Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum

TANK with 20 tons ,25 tons .

Powder product :

Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg .

Drum of 25 kg and 50 kg
Port
Shanghai port,Qingdao port,or any China Main Port
Lead Time:
Quantity(Kilograms) 1 - 100 101 - 1000 >1000
Est. Time(days) 2 2 To be negotiated

Property

CAS No.: 65-49-6 Formula: C7H7NO3 Molecular Weight: 153.13500

Description

4-Aminosalicylic acid (para-aminosalicylic acid or PAS) is an antibiotic used to treat tuberculosis. This organic compound has also been use since the 1940s for the treatment of inflammatory bowel diseases (IBDs), where it has shown greater potency in ulcerative colitis and Crohn's disease. It is thought to act via NF-κB (nuclear factor-kappa B) inhibition and free radical scavenging. The closely related chemical compound 5-aminosalicylic acid, sold under the name mesalazine, also has medical uses.
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Basic Info

Chemical Name	4-aminosalicylic acid
Synonyms	p-aminosalicylic acid; PASK; Apas; PAS; 4-amino-salicylic acid; 4-Aminosalicylic acid; Pasa; Benzoic acid, 4-amino-2-hydroxy-; Aminox; PAS-C; Pasem; 4-Asa; A 1909; para-amino salicylic acid; Paser;
CAS No.	65-49-6
Molecular Formula	C7H7NO3
Molecular Weight	153.13500
PSA	83.55000
LogP	1.25380

Properties

Appearance & Physical State	Minute crystals from alc. Odorless, or has slight acetous odor.
Density	1.545 g/cm3
Boiling Point	347ºC
Melting Point	135-145ºC
Flash Point	184.1ºC
Water Solubility	2 g/L (20 ºC)
Stability	Stable under normal temperatures and pressures.
Storage Condition	Store at 0-5ºC

Safety Info

RTECS	VO1225000
Safety Statements	S26-S37/39
HS Code	29225000
WGK Germany	2
RIDADR	UN 1789 8/PG 3
Risk Statements	R36/37/38
Hazard Codes	Xi
Caution Statement	P305 + P351 + P338
Signal Word	Warning
Hazard Declaration	H319
Symbol	GHS07

Synthesis Route

4-Nitrosalicylic acid→4-aminosalicylic acid
3-aminophenol→4-aminosalicylic acid
1,5-divinylhexamethyltrisiloxane→4-aminosalicylic acid

Precursor

1,5-divinylhexamethyltrisiloxane
potassium hydrogencarbonate
4-Nitrosalicylic acid
resorcinol

Downstream Product

methyl 2-methoxy-4-(methylamino)benzoate
4-acetamidosalicylic acid
Methyl 4-acetamido-5-chloro-2-ethoxybenzoate
3-amino-2-((E)-phenyldiazenyl)-6-(phenyldiazenyl)phenol

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